SCHEMBL312680

SCHEMBL312680

C=C[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
BTK Q06187 1/20 0.33
MAPT P10636 2/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
GAA P10253 2/20 0.31
EPHX2 P34913 1/20 0.31
CACNA1H O95180 1/20 0.30
CTSK P43235 1/20 0.30
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12772356 1.00 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT
SCHEMBL31287272 1.00 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT
SCHEMBL1537645 1.00 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT
SCHEMBL6050963 1.00 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT
SCHEMBL12530114 1.00 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT
SCHEMBL380051 1.00 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT
SCHEMBL2617514 1.00 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT
SCHEMBL2617503 1.00 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT
SCHEMBL8002198 1.00 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT
SCHEMBL1673987 0.90 MEN1 (0.38) MEN1MAPK1KMT2ABTKMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113088198-A Shoe polish prepared from lanolin extract and preparation method thereof 浙江花园营养科技有限公司 2021-07-09 CN claimed
CN-119930740-A Dipeptide compound, chimeric molecule based on dipeptide compound and application of dipeptide compound 西南交通大学 2025-05-06 CN disclosed
US-12227520-B2 Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use GILEAD SCIENCES, INC. (US) 2025-02-18 US disclosed
CN-119264505-A High-resilience soft foaming polyethylene material and preparation method thereof 杭州锦煌科技有限公司 2025-01-07 CN disclosed
US-20230203061-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES, INC. 2023-06-29 US disclosed
US-20230027019-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES INC (US) 2023-01-26 US disclosed
EP-4122537-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE Gilead Sciences, Inc. (US) 2023-01-25 EP disclosed
US-11548902-B1 Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use GILEAD SCIENCES, INC. (US) 2023-01-10 US disclosed
EP-3938047-B1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES INC (US) 2022-06-22 EP disclosed
CN-114560857-A Pyrimidopyridine compound and application thereof in medicine 广东东阳光药业有限公司 2022-05-31 CN disclosed
US-20050143316-A1 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY 2005-06-30 US disclosed
WO-2005051410-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2005-06-09 WO disclosed
US-6878722-B2 Substituted cycloalkyl P1′ hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2005-04-12 US disclosed
US-6869964-B2 Heterocyclicsulfonamide hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2005-03-22 US disclosed
EP-1505945-A2 SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS Bristol-Myers Squibb Pharma Company (US) 2005-02-16 EP disclosed
US-20040106559-A1 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY 2004-06-03 US disclosed
WO-2004043339-A2 SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-05-27 WO disclosed
US-20040077551-A1 Substituted cycloalkyl P1' hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY 2004-04-22 US disclosed
US-20040072761-A1 Heterocyclicsulfonamide hepatitis C virus inhibitors CAMPBELL JEFFREY ALLEN (US) 2004-04-15 US disclosed
US-20040048802-A1 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY 2004-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040072761-A1 Heterocyclicsulfonamide hepatitis C virus inhibitors HCCS, ANPEP, DNPEP MEN1 4196/4885MAPK1 3138/4885KMT2A 4022/4885
US-12227520-B2 Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use ZYX, CCNY, XDH MEN1 3841/4885MAPK1 4169/4885KMT2A 2126/4885
US-11548902-B1 Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use ZYX, CCNY, XDH MEN1 3841/4885MAPK1 4169/4885KMT2A 2126/4885
US-20230203061-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE ZYX, CCNY, XDH MEN1 3841/4885MAPK1 4169/4885KMT2A 2126/4885
US-20230027019-A1 BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE ZYX, CCNY, XDH MEN1 3841/4885MAPK1 4169/4885KMT2A 2126/4885
US-20050143316-A1 Hepatitis C virus inhibitors HAVCR2, HCCS, CTRB1 MEN1 4820/4885MAPK1 2557/4885KMT2A 4052/4885
US-20040106559-A1 Hepatitis C virus inhibitors HAVCR2, HCCS, RNASE1 MEN1 4817/4885MAPK1 1573/4885KMT2A 4220/4885
US-20040048802-A1 Hepatitis C virus inhibitors HAVCR2, ZC3HAV1, VIP MEN1 4575/4885MAPK1 3677/4885KMT2A 4483/4885
US-20040077551-A1 Substituted cycloalkyl P1' hepatitis C virus inhibitors HAVCR2, ANPEP, ENPEP MEN1 4174/4885MAPK1 3703/4885KMT2A 4708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.