Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.86 |
| ▸ | MAOA | P21397 | 5/20 | 0.69 |
| ▸ | MAOB | P27338 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | STAT3 | P40763 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16740649 | 1.00 | PTPN1 (0.86) | PTPN1MAOAMAOBMAPTNPC1 | |
| SCHEMBL31745319 | 0.92 | PTPN1 (0.73) | PTPN1MAOAMAOBMAPTNPC1 | |
| SCHEMBL7485310 | 0.84 | PTPN1 (0.77) | PTPN1MAOBMAPTNPC1RAB9A | |
| SCHEMBL7485313 | 0.84 | PTPN1 (0.77) | PTPN1MAOBMAPTNPC1RAB9A | |
| SCHEMBL108665 | 0.84 | MAPT (0.79) | PTPN1MAOAMAOBMAPTNPC1 | |
| SCHEMBL28553855 | 0.84 | MAPT (0.79) | PTPN1MAOAMAOBMAPTNPC1 | |
| SCHEMBL4728402 | 0.83 | STAT3 (0.84) | MAOAMAOBMAPTNPC1RAB9A | |
| SCHEMBL4728397 | 0.83 | STAT3 (0.84) | MAOAMAOBMAPTNPC1RAB9A | |
| SCHEMBL28549142 | 0.82 | MAOA (0.76) | MAOAMAOBMAPTNPC1RAB9A | |
| SCHEMBL15404139 | 0.81 | MAPT (1.00) | MAOAMAOBMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015075051-A1 | ALLOSTERIC INHIBITORS OF ATYPICAL PROTEIN KINASES C | UNIVERSITAET DES SAARLANDES (DE) | 2015-05-28 | — | — | WO | disclosed |