Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 17/20 | 1.00 |
| ▸ | ESD | P10768 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293086 | 0.84 | PRKCZ (0.72) | PRKCZESDMEN1HSP90AA1KMT2A | |
| SCHEMBL16740583 | 0.84 | PRKCZ (1.00) | PRKCZMEN1HSP90AA1GAAKMT2A | |
| SCHEMBL6292757 | 0.78 | PRKCZ (0.62) | PRKCZESDMEN1HSP90AA1GAA | |
| SCHEMBL16740602 | 0.78 | PRKCZ (1.00) | PRKCZMEN1HSP90AA1GAAKMT2A | |
| SCHEMBL27955197 | 0.72 | PRKCZ (0.90) | PRKCZMEN1HSP90AA1GAAKMT2A | |
| SCHEMBL16740610 | 0.71 | PRKCZ (1.00) | PRKCZ | |
| SCHEMBL16740621 | 0.70 | PRKCZ (0.60) | PRKCZMEN1HSP90AA1KMT2A | |
| SCHEMBL6294114 | 0.70 | CA1 (0.56) | PRKCZESDMEN1HSP90AA1GAA | |
| SCHEMBL6293056 | 0.70 | CA1 (0.56) | PRKCZMEN1HSP90AA1GAAKMT2A | |
| SCHEMBL9628590 | 0.70 | PRKCZ (1.00) | PRKCZMEN1HSP90AA1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015075051-A1 | ALLOSTERIC INHIBITORS OF ATYPICAL PROTEIN KINASES C | UNIVERSITAET DES SAARLANDES (DE) | 2015-05-28 | — | — | WO | disclosed |