SCHEMBL16741

SCHEMBL16741

NP(O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3667891 1.00
Hydrazine SCHEMBL4918027 0.93
Hydrochloric Acid SCHEMBL3442206 0.93
Hydrogen Sulfide SCHEMBL3358284 0.93
Hydroxyamine SCHEMBL272868 0.93
SCHEMBL4594980 0.93
Methane SCHEMBL7938760 0.93
SCHEMBL7901642 0.93
Phosphine SCHEMBL20595760 0.93
SCHEMBL3358625 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 111231 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146060-A1 PHOSPHORAMIDITE CONJUGATES AND METHODS OF FORMING SYNTHETIC OLIGONUCLEOTIDES THEREFROM CARNEGIE MELLON UNIVERSITY (US) 2026-05-28 US claimed
EP-4746924-A1 NON-NATURAL BUILDING BLOCKS FOR ENHANCED TRANSLATION AND STABILITY OF MRNA Eleven Therapeutics Ltd (IL) 2026-05-27 EP claimed
US-12637403-B2 Access to chiral bisphenol (BPOL) ligands through desymmetrizing asymmetric ortho-selective mono-halogenation THE CHINESE UNIVERSITY OF HONG KONG (CN) 2026-05-26 US claimed
CN-122079818-A Open chain imine axial chiral compound and synthesis method thereof 2026-05-26 CN claimed
CN-116368146-B Novel ligands for asialoglycoprotein receptors SAI NUOFEI (FR) 2026-05-26 CN claimed
CN-122079806-A Method for preparing chiral benzhydrol compound by rhodium-catalyzed asymmetric hydrogenation of o-amidobenzophenone and application of chiral benzhydrol compound 2026-05-26 CN claimed
CN-122071417-A Method for preparing chiral amine compound by asymmetric hydrogenation of ruthenium catalytic imine 中国科学院大连化学物理研究所 2026-05-22 CN claimed
WO-2026106815-A1 Z-INDUCING CHIMERA COMPOSITION RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2026-05-21 WO claimed
CN-119462752-B Imidazole-phosphoramidite bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-phosphoramidite bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-122036787-A Synthesis of cyclooctenamine linker and application of cyclooctenamine linker in coupled medicine 苏州盛诺维生物科技有限公司 2026-05-15 CN claimed
EP-0224578-A4 COMPOSITIONS AND METHODS FOR FUNCTIONALIZING NUCLEIC ACIDS. AMGEN (US) 1987-10-19 EP claimed
EP-0235046-A1 DNA probe specific for the male genomes of ruminants, their preparation and use INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, Etablissement public dit: (FR) 1987-09-02 EP claimed
EP-0224578-A1 COMPOSITIONS AND METHODS FOR FUNCTIONALIZING NUCLEIC ACIDS. AMGEN (US) 1987-06-10 EP claimed
EP-0216357-A2 Phosphoramidite compounds and process for production thereof NIPPON ZEON CO., LTD. (JP) 1987-04-01 EP claimed
WO-1986007363-A1 COMPOSITIONS AND METHODS FOR FUNCTIONALIZING NUCLEIC ACIDS AMGEN (US) 1986-12-18 WO claimed
EP-0196101-A2 Purification of synthetic oligomers CHIRON CORPORATION (US) 1986-10-01 EP claimed
EP-0191659-A1 Derivatives of adenosine nucleosides, their preparation and their biological use INSTITUT PASTEUR (FR) 1986-08-20 EP claimed
EP-0020297-B1 CYCLIC PHOSPHORIC ACID ESTER AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS STABILIZERS CIBA-GEIGY AG (CH) 1983-04-13 EP claimed
US-4202817-A FROM A PHOSPHITE AMIDE OF 6-AMINO-PENICILLANIC OR CEPHALOSPORANIC ACID WITH A P-HYDROXY-PHENYLGLYCYL HALIDE IN AN APROTIC SOLVENT, ALSO A PHOSPHITE HALIDE SCAVENGER NOVO INDUSTRI A/S (DK) 1980-05-13 US claimed
US-4049689-A FROM AN ALKYL HALIDE AND TIN IN A LIQUID ACID AMIDE COMMER S.R.L. (IT) 1977-09-20 US claimed