⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667891 | 0.93 | — | — | |
| SCHEMBL16741 | 0.93 | — | — | |
| SCHEMBL3358625 | 0.86 | — | — | |
| Hydroxyamine SCHEMBL272868 | 0.86 | — | — | |
| Hydrazine SCHEMBL4918027 | 0.86 | — | — | |
| SCHEMBL4594980 | 0.86 | — | — | |
| Phosphine SCHEMBL20595760 | 0.86 | — | — | |
| SCHEMBL7901642 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL3442206 | 0.86 | — | — | |
| Phosphine SCHEMBL3390155 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077228-A2 | DOUBLE-STRANDED OLIGONUCLEOTIDES AND METHODS OF USE | CITY OF HOPE (US) | 2024-04-11 | — | — | WO | disclosed |
| WO-2024059754-A1 | POLYTHIOLATED LINKERS FOR STABLE NANOPARTICLE SUSPENSIONS AND USES THEREOF | QUANTAPORE, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| US-9969764-B2 | Dithiolane functionalized nucleoside amidites and supports for stronger immobilization of bio-molecules on solid surfaces | CHEMGENES CORPORATION | 2018-05-15 | — | — | US | disclosed |
| US-20170037076-A1 | DITHIOLANE FUNCTIONALIZED NUCLEOSIDE AMIDITES AND SUPPORTS FOR STRONGER IMMOBILIZATION OF BIO-MOLECULES ON SOLID SURFACES | CHEMGENES CORPORATION | 2017-02-09 | — | — | US | disclosed |
| CN-106061981-A | Polynucleotide constructs having disulfide groups | 索尔斯蒂斯生物有限公司 | 2016-10-26 | — | — | CN | disclosed |
| US-9441002-B2 | Dithiolane based thiol modifier for labeling and stronger immobilization of bio-molecules on solid surfaces | CHEMGENES CORPORATION (US) | 2016-09-13 | — | — | US | disclosed |
| EP-3060572-A1 | DITHIOLANE FUNCTIONALIZED NUCLEOSIDE AMIDITES AND SUPPORTS FOR STRONGER IMMOBILIZATION OF BIO-MOLECULES ON SOLID SURFACES | Chemgenes Corporation (US) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015061507-A1 | DITHIOLANE FUNCTIONALIZED NUCLEOSIDE AMIDITES AND SUPPORTS FOR STRONGER IMMOBILIZATION OF BIO-MOLECULES ON SOLID SURFACES | CHEMGENES CORPORATION (US) | 2015-04-30 | — | — | WO | disclosed |
| US-20140142253-A1 | Dithiolane Based Thiol Modifier For Labeling and Stronger Immobilization of Bio-Molecules On Solid Surfaces | CHEMGENES CORPORATION (US) | 2014-05-22 | — | — | US | disclosed |
| US-8530156-B2 | Chemically cleavable phosphoramidite linkers for sequencing by ligation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-09-10 | — | — | US | disclosed |
| EP-1355672-A2 | CONJUGATES OF GLYCOSYLATED/GALACTOSYLATED PEPTIDE, BIFUNCTIONAL LINKER, AND NUCLEOTIDIC MONOMERS/POLYMERS, AND RELATED COMPOSITIONS AND METHODS OF USE | Cell Works Inc. (US) | 2003-10-29 | — | — | EP | disclosed |
| US-20030087271-A1 | Method for the amplification and detection of a nucleic acid fragment of interest | EBERSOLE RICHARD C (US) | 2003-05-08 | — | — | US | disclosed |
| US-20030032584-A1 | Conjugates of glycosylated/galactosylated peptide, bifunctional linker, and nucleotidic monomers/polymers, and related compositions and method of use | CELL WORKS INC. (US) | 2003-02-13 | — | — | US | disclosed |
| WO-2002043771-A2 | CONJUGATES OF GLYCOSYLATED/GALACTOSYLATED PEPTIDE | CELL WORKS INC. (US) | 2002-06-06 | — | — | WO | disclosed |
| EP-0954603-A2 | METHOD AND REAGENT FOR DETECTING MULTIPLE NUCLEIC ACID SEQUENCES IN A TEST SAMPLE | Abbott Laboratories (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5955268-A | DETECTING TARGET IN SAMPLE BY AMPLIFICATION, THEN HYBRIDIZATION TO LABELED CAPTURE PRODES IMMOBILIZED ON SUPPORT, DETECTING CHANGE IN SIGNAL | ABBOTT LABORATORIES (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0892856-A1 | A METHOD FOR THE AMPLIFICATION AND DETECTION OF A NUCLEIC ACID FRAGMENT OF INTEREST | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997032044-A9 | A METHOD FOR THE AMPLIFICATION AND DETECTION OF A NUCLEIC ACID FRAGMENT OF INTEREST | — | 1997-11-20 | — | — | WO | disclosed |
| WO-1997041256-A2 | METHOD AND REAGENT FOR DETECTING MULTIPLE NUCLEIC ACID SEQUENCES IN A TEST SAMPLE | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | disclosed |
| WO-1997032044-A1 | A METHOD FOR THE AMPLIFICATION AND DETECTION OF A NUCLEIC ACID FRAGMENT OF INTEREST | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |