Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 19/20 | 0.57 |
| ▸ | ARG2 | P78540 | 13/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894933 | 0.84 | ARG1 (0.57) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894980 | 0.83 | ARG1 (0.56) | ARG1ARG2 | |
| SCHEMBL10008908 | 0.79 | ARG1 (0.55) | ARG1ARG2 | |
| SCHEMBL894921 | 0.79 | ARG1 (0.79) | ARG1ARG2 | |
| SCHEMBL12294006 | 0.78 | ARG1 (0.61) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL895047 | 0.78 | ARG1 (0.77) | ARG1ARG2 | |
| SCHEMBL895647 | 0.78 | ARG1 (0.60) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL895379 | 0.77 | ARG1 (0.58) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL895023 | 0.77 | ARG1 (0.76) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL895165 | 0.76 | ARG1 (0.57) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040703-B2 | Inhibitors of arginase and their therapeutic applications | MARS, INCORPORATED (US) | 2015-05-26 | — | — | US | disclosed |