Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17072557 | 1.00 | DRD1 (0.40) | DRD1 | |
| SCHEMBL16745328 | 1.00 | DRD1 (0.40) | DRD1 | |
| SCHEMBL16745301 | 0.97 | DRD1 (0.40) | DRD1 | |
| SCHEMBL16745297 | 0.94 | DRD1 (0.46) | DRD1 | |
| SCHEMBL17070585 | 0.93 | DRD1 (0.39) | DRD1 | |
| SCHEMBL17070586 | 0.93 | DRD1 (0.39) | DRD1 | |
| SCHEMBL16745512 | 0.93 | DRD1 (0.36) | DRD1 | |
| SCHEMBL16745279 | 0.93 | DRD1 (0.39) | DRD1 | |
| SCHEMBL16745566 | 0.93 | DRD1 (0.36) | DRD1 | |
| SCHEMBL16812574 | 0.93 | DRD1 (0.39) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127320-A1 | INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 四川大学 | 2022-06-23 | — | — | WO | claimed |
| CN-114423764-A | Intermediate, preparation method and application thereof | 四川大学 | 2022-04-29 | — | — | CN | claimed |
| CN-114423764-B | Intermediate, preparation method and application thereof | 四川大学 | 2023-03-17 | — | — | CN | disclosed |
| WO-2022127320-A1 | INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 四川大学 | 2022-06-23 | — | — | WO | disclosed |
| CN-114423764-A | Intermediate, preparation method and application thereof | 四川大学 | 2022-04-29 | — | — | CN | disclosed |
| US-20200392150-A1 | Diaryl-B-Lactam Compound and Preparation Method and Pharmaceutical Use Thereof | FUDAN UNIVERSITY (CN) | 2020-12-17 | — | — | US | disclosed |
| WO-2017167183-A1 | DIARYL-Β-LACTAM COMPOUND AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 复旦大学 | 2017-10-05 | — | — | WO | disclosed |
| US-9527862-B2 | Compounds of chiral aromatic spiroketal diphosphine ligands, preparation methods and uses thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-12-27 | — | — | US | disclosed |
| US-9527862-B2 | Compounds of chiral aromatic spiroketal diphosphine ligands, preparation methods and uses thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-12-27 | — | — | US | disclosed |
| US-9518014-B2 | Process for synthesis of ezetimibe and intermediates used in said process | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-12-13 | — | — | US | disclosed |
| EP-2876102-B1 | PROCESS FOR SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USED IN SAID PROCESS | SHANGHAI INST ORGANIC CHEMISTRY CAS (CN) | 2016-12-07 | — | — | EP | disclosed |
| US-20150252055-A1 | COMPOUNDS OF CHIRAL AROMATIC SPIROKETAL DIPHOSPHINE LIGANDS, PREPARATION METHODS AND USES THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-09-10 | — | — | US | disclosed |
| US-20150252055-A1 | COMPOUNDS OF CHIRAL AROMATIC SPIROKETAL DIPHOSPHINE LIGANDS, PREPARATION METHODS AND USES THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-09-10 | — | — | US | disclosed |
| US-20150166479-A1 | PROCESS FOR SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USED IN SAID PROCESS | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-06-18 | — | — | US | disclosed |
| EP-2876108-A1 | COMPOUNDS OF CHIRAL AROMATIC SPIROKETAL DIPHOSPHINE LIGANDS, PREPARATION METHODS AND USES THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2015-05-27 | — | — | EP | disclosed |
| EP-2876102-A1 | PROCESS FOR SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USED IN SAID PROCESS | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2015-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166479-A1 | PROCESS FOR SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USED IN SAID PROCESS | HMGCR, COASY, APOB | DRD1 4195/4885 |
| US-20200392150-A1 | Diaryl-B-Lactam Compound and Preparation Method and Pharmaceutical Use Thereof | PEPD, SQLE, BACE1 | DRD1 3562/4885 |
| US-20150252055-A1 | COMPOUNDS OF CHIRAL AROMATIC SPIROKETAL DIPHOSPHINE LIGANDS, PREPARATION METHODS AND USES THEREOF | DDT, DPYD, RECQL | DRD1 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.