Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26014617 | 1.00 | KCNA5 (0.50) | KCNA5CYP3A4CYP2C19SMN1; SMN2GAA | |
| SCHEMBL26014606 | 1.00 | KCNA5 (0.50) | KCNA5CYP3A4CYP2C19SMN1; SMN2GAA | |
| SCHEMBL26014619 | 0.94 | KCNA5 (0.50) | KCNA5CYP3A4CYP2C19SMN1; SMN2GAA | |
| SCHEMBL26014618 | 0.94 | KCNA5 (0.50) | KCNA5CYP3A4CYP2C19SMN1; SMN2GAA | |
| SCHEMBL5175578 | 0.84 | SMN1; SMN2 (0.46) | KCNA5SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL10719115 | 0.84 | KCNA5 (0.45) | KCNA5SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL16746019 | 0.74 | GAA (0.35) | KCNA5SMN1; SMN2GAASLC18A3 | |
| SCHEMBL22375302 | 0.74 | GAA (0.35) | KCNA5SMN1; SMN2GAASLC18A3 | |
| SCHEMBL22375301 | 0.74 | GAA (0.35) | KCNA5SMN1; SMN2GAASLC18A3 | |
| SCHEMBL16746020 | 0.74 | GAA (0.35) | KCNA5SMN1; SMN2GAASLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340013-A1 | POLYPEPTIDES AND METHODS | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-10-26 | — | — | US | disclosed |
| US-11732001-B2 | Methods of incorporating an amino acid comprising a BCN group into a polypeptide using an orthogonal codon encoding it and an orthogonal pylrs synthase | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-08-22 | — | — | US | disclosed |
| US-20150148525-A1 | METHODS OF INCORPORATING AN AMINO ACID COMPRISING A BCN GROUP INTO A POLYPEPTIDE USING AN ORTHOGONAL CODON ENCODING IT AND AN ORTHORGONAL PYLRS SYNTHASE | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230340013-A1 | POLYPEPTIDES AND METHODS | BCAT1, BCDIN3D, NPY1R | KCNA5 3816/4885CYP3A4 3531/4885CYP2C19 3314/4885 |
| US-11732001-B2 | Methods of incorporating an amino acid comprising a BCN group into a polypeptide using an orthogonal codon encoding it and an orthogonal pylrs synthase | COASY, BCAT1, FARSA | KCNA5 4256/4885CYP3A4 3454/4885CYP2C19 2631/4885 |
| US-20150148525-A1 | METHODS OF INCORPORATING AN AMINO ACID COMPRISING A BCN GROUP INTO A POLYPEPTIDE USING AN ORTHOGONAL CODON ENCODING IT AND AN ORTHORGONAL PYLRS SYNTHASE | BCAT1, BCDIN3D, YARS1 | KCNA5 3641/4885CYP3A4 3496/4885CYP2C19 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.