SCHEMBL1674736

SCHEMBL1674736

COCCNC(=O)C1CCCCCCCCCCC1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.57
NAAA Q02083 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
EPHX2 P34913 2/20 0.56
NPC1 O15118 1/20 0.56
PKM P14618 1/20 0.56
RAB9A P51151 1/20 0.56
MAPT P10636 1/20 0.55
HPGD P15428 2/20 0.52
KDM4E B2RXH2 1/20 0.52
EPHX1 P07099 1/20 0.52
CNR2 P34972 2/20 0.50
CNR1 P21554 1/20 0.50
CYP3A4 P08684 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH1A1 P00352 1/20 0.48
CYP2C19 P33261 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30832082 1.00 KMT2A (0.58) KMT2AMEN1NAAASMN1; SMN2EPHX2
SCHEMBL24116980 1.00 KMT2A (0.58) KMT2AMEN1NAAASMN1; SMN2EPHX2
SCHEMBL31524234 0.98 KMT2A (0.56) KMT2AMEN1NAAASMN1; SMN2EPHX2
SCHEMBL16799726 0.90 MAPT (0.59) KMT2AMEN1SMN1; SMN2EPHX2NPC1
SCHEMBL22652025 0.89 NAAA (0.63) KMT2AMEN1NAAASMN1; SMN2EPHX2
SCHEMBL13201338 0.84 POLB (0.65) KMT2AMEN1EPHX2NPC1MAPT
SCHEMBL24244844 0.83 SMN1; SMN2 (0.58) KMT2AMEN1NAAASMN1; SMN2EPHX2
SCHEMBL3915204 0.82 MAPT (0.52) KMT2AMEN1EPHX2NPC1MAPT
SCHEMBL3402321 0.82 MAPT (0.52) KMT2AMEN1EPHX2NPC1MAPT
SCHEMBL10001620 0.82 NAAA (0.58) KMT2AMEN1NAAASMN1; SMN2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1377613-B1 METHOD OF MAKING INTERPOLYMERS AND PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-19 EP disclosed
EP-1412398-B1 HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-24 EP disclosed
US-7999039-B2 Catalytic polymerization of olefinic monomers in the presence of a high molecular weight catalyst and a low molecular weight catalyst in a polymerization reactor system; high melt strength DOW GLOBAL TECHNOLOGIES LLC (US) 2011-08-16 US disclosed
US-RE42276-E1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC (US) 2011-04-05 US disclosed
US-7271221-B2 Method of making interpolymers and products made therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2007-09-18 US disclosed
US-20050187350-A1 Method of making interpolymers and products made therefrom DOW GLOBAL TECHNOLOGIES, INC. (US) 2005-08-25 US disclosed
US-6924342-B2 Method of making interpolymers and products made therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2005-08-02 US disclosed
US-20050065286-A1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC 2005-03-24 US disclosed
US-20050020778-A1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC 2005-01-27 US disclosed
EP-1412398-A2 HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2004-04-28 EP disclosed
EP-1377613-A2 METHOD OF MAKING INTERPOLYMERS AND PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-01-07 EP disclosed
US-20030088037-A1 Method of making interpolymers and products made therefrom THE DOW CHEMICAL COMPANY (US) 2003-05-08 US disclosed
US-20030050411-A1 Use of polar monomers in olefin polymerization and polymers thereof DOW GLOBAL TECHNOLOGIES INC. 2003-03-13 US disclosed
WO-2002100906-A1 USE OF POLAR MONOMERS IN OLEFIN POLYMERIZATION AND POLYMERS THEREOF DOW GLOBAL TECHNOLOGIES INC. (US) 2002-12-19 WO disclosed
WO-2002074817-A2 METHOD OF MAKING INTERPOLYMERS AND PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2002-09-26 WO disclosed
WO-2002074816-A2 HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2002-09-26 WO disclosed
US-5844037-A Thermoplastic polymer compositions with modified electrical conductivity THE DOW CHEMICAL COMPANY (US) 1998-12-01 US disclosed