Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 9/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16747497 | 0.99 | VDR (0.42) | VDRCYP24A1CYP4F2CYP4A11PPARG | |
| SCHEMBL16747519 | 0.91 | VDR (0.43) | VDRCYP24A1CYP4F2CYP4A11PPARG | |
| SCHEMBL16747380 | 0.91 | VDR (0.44) | VDRCYP24A1CYP4F2CYP4A11PPARG | |
| SCHEMBL16747384 | 0.90 | VDR (0.45) | VDRCYP24A1PPARGPPARASPHK2 | |
| SCHEMBL16747496 | 0.89 | VDR (0.45) | VDRCYP24A1PPARGPPARASPHK2 | |
| SCHEMBL16747533 | 0.89 | VDR (0.45) | VDRCYP24A1PPARGPPARASPHK2 | |
| SCHEMBL16747507 | 0.88 | VDR (0.41) | VDRCYP24A1CYP4F2CYP4A11PPARG | |
| SCHEMBL16747498 | 0.87 | VDR (0.43) | VDRCYP24A1CYP4F2CYP4A11PPARG | |
| SCHEMBL18134443 | 0.85 | VDR (0.45) | VDRCYP24A1CYP4F2CYP4A11PPARG | |
| SCHEMBL16747398 | 0.85 | VDR (0.38) | VDRCYP24A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3072873-B1 | VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST | UNIV SANTIAGO COMPOSTELA (ES) | 2019-02-20 | — | — | EP | disclosed |
| EP-3072873-A1 | VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST | Universidade De Santiago De Compostela (ES) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015075291-A1 | VITAMIN D ANALOGUES OF PHARMACEUTICAL INTEREST | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2015-05-28 | — | — | WO | disclosed |