Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915490 | 0.88 | MAPT (0.40) | MAPTSMPD1ALDH1A1ACRPOLB | |
| SCHEMBL16748687 | 0.87 | HPGD (0.43) | MAPTSMPD1ALDH1A1CNR2NPC1 | |
| SCHEMBL16747528 | 0.78 | CYP1A2 (0.39) | MAPTSMPD1L3MBTL1CNR2NPC1 | |
| SCHEMBL9915483 | 0.78 | MAPT (0.47) | MAPTSMPD1ALDH1A1ACRPOLB | |
| SCHEMBL9915495 | 0.75 | SMPD1 (0.41) | MAPTSMPD1ALDH1A1CNR2HPGD | |
| SCHEMBL8214120 | 0.74 | MAPT (0.47) | MAPTSMPD1ALDH1A1ACRPOLB | |
| SCHEMBL11994109 | 0.74 | SMPD1 (0.43) | MAPTSMPD1ALDH1A1ACRL3MBTL1 | |
| SCHEMBL16748640 | 0.74 | SMPD1 (0.38) | MAPTSMPD1TP53SMN1; SMN2TSHR | |
| SCHEMBL15468406 | 0.74 | SMPD1 (0.70) | MAPTSMPD1ACRTP53NPC1 | |
| SCHEMBL12966382 | 0.73 | HSP90AA1 (0.46) | MAPTSMPD1ALDH1A1TP53CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646436-B1 | MONOBACTAMS | PFIZER (US) | 2015-05-27 | — | — | EP | disclosed |