Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 9/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915490 | 0.88 | MAPT (0.40) | SMPD1ALDH1A1MAPTCNR2FAAH | |
| SCHEMBL16748687 | 0.87 | HPGD (0.43) | SMPD1ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL14124870 | 0.81 | SMPD1 (0.44) | SMPD1ALDH1A1 | |
| SCHEMBL9915473 | 0.81 | GAA (0.42) | SMPD1S1PR3 | |
| SCHEMBL9915358 | 0.80 | S1PR3 (0.37) | ALDH1A1S1PR3 | |
| SCHEMBL9915362 | 0.77 | XDH (0.41) | ALDH1A1S1PR3 | |
| SCHEMBL16748690 | 0.75 | MAPT (0.41) | SMPD1ALDH1A1MAPTHPGDCNR2 | |
| SCHEMBL9915470 | 0.74 | SMPD1 (0.37) | SMPD1MAPTHTT | |
| SCHEMBL92482 | 0.73 | CNR2 (0.64) | ALDH1A1HPGDCNR2FAAH | |
| SCHEMBL12225702 | 0.71 | CNR2 (0.43) | SMPD1ALDH1A1MAPTHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302542-A1 | MONOBACTAMS | PFIZER INC | 2012-11-29 | — | — | US | disclosed |
| WO-2012073138-A1 | MONOBACTAMS | PFIZER INC. (US) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302542-A1 | MONOBACTAMS | MGAM, MGAM2, BPGM | SMPD1 2714/4885ALDH1A1 1829/4885MAPT 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.