Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 17/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23042158 | 1.00 | TNK2 (0.42) | TNK2IGF1RFGFR1FGFR2 | |
| SCHEMBL25381579 | 0.90 | TNK2 (0.38) | TNK2IGF1RFGFR1FGFR2 | |
| SCHEMBL18099736 | 0.85 | TNK2 (0.41) | TNK2IGF1RFGFR1FGFR2 | |
| SCHEMBL17892737 | 0.84 | TNK2 (0.37) | TNK2IGF1R | |
| SCHEMBL17892736 | 0.84 | TNK2 (0.37) | TNK2IGF1R | |
| SCHEMBL400077 | 0.84 | TNK2 (0.46) | TNK2IGF1RFGFR1FGFR2 | |
| SCHEMBL16748884 | 0.83 | TNK2 (0.56) | TNK2IGF1RFGFR1FGFR2 | |
| SCHEMBL398540 | 0.83 | TNK2 (0.42) | TNK2IGF1RFGFR1FGFR2 | |
| SCHEMBL19619152 | 0.83 | TNK2 (0.56) | TNK2IGF1RFGFR1FGFR2 | |
| SCHEMBL1129050 | 0.83 | TNK2 (0.42) | TNK2IGF1RFGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822120-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-11-21 | — | — | US | disclosed |
| US-9822120-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-11-21 | — | — | US | disclosed |
| US-20160280711-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2016-09-29 | — | — | US | disclosed |
| US-20160280711-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2016-09-29 | — | — | US | disclosed |
| WO-2015074138-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280711-A1 | Protein Kinase Inhibitors | TEC, LCK, SRC | TNK2 43/4885IGF1R 1739/4885FGFR1 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.