Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 17/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748884 | 1.00 | TNK2 (0.56) | TNK2IGF1RFGFR2FGFR1 | |
| SCHEMBL22236165 | 0.89 | IGF1R (0.48) | TNK2IGF1RFGFR2FGFR1 | |
| SCHEMBL14630053 | 0.88 | BTK (0.49) | TNK2IGF1RFGFR2 | |
| SCHEMBL14630052 | 0.88 | BTK (0.49) | TNK2IGF1RFGFR2 | |
| SCHEMBL14536932 | 0.86 | TNK2 (0.56) | TNK2FGFR2FGFR1 | |
| SCHEMBL12165227 | 0.86 | TNK2 (0.56) | TNK2FGFR2FGFR1 | |
| SCHEMBL16748879 | 0.85 | TNK2 (0.52) | TNK2IGF1RFGFR2FGFR1 | |
| SCHEMBL19264081 | 0.84 | TNK2 (0.57) | TNK2IGF1RFGFR2FGFR1 | |
| SCHEMBL23042158 | 0.83 | TNK2 (0.42) | TNK2IGF1RFGFR2FGFR1 | |
| SCHEMBL398601 | 0.83 | TNK2 (0.56) | TNK2IGF1RFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822120-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-11-21 | — | — | US | disclosed |