Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 1/20 | 0.60 |
| ▸ | CCR1 | P32246 | 1/20 | 0.60 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CALCA | P06881 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749035 | 0.88 | KCNE1 (0.61) | KCNE1CCR1KCNQ1KMT2AMEN1 | |
| SCHEMBL18138316 | 0.82 | KCNE1 (0.67) | KCNE1CCR1KCNQ1KMT2AMEN1 | |
| SCHEMBL5315124 | 0.81 | KCNE1 (0.66) | KCNE1CCR1KCNQ1KMT2AMEN1 | |
| SCHEMBL13041229 | 0.80 | KCNE1 (0.69) | KCNE1CCR1KCNQ1KMT2AMEN1 | |
| SCHEMBL18138315 | 0.79 | KCNE1 (0.72) | KCNE1CCR1KCNQ1KMT2AMEN1 | |
| SCHEMBL1150993 | 0.79 | KCNE1 (0.72) | KCNE1CCR1KCNQ1KMT2AMEN1 | |
| SCHEMBL1150537 | 0.79 | KCNE1 (0.74) | KCNE1CCR1KCNQ1KMT2AMEN1 | |
| SCHEMBL5314622 | 0.79 | KCNE1 (0.67) | KCNE1CCR1KCNQ1KMT2AMEN1 | |
| SCHEMBL19306601 | 0.78 | KCNE1 (0.75) | KCNE1CCR1KCNQ1KMT2AMEN1 | |
| SCHEMBL18832229 | 0.77 | KCNE1 (0.60) | KCNE1CCR1KCNQ1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015077774-A1 | INHIBITORS OF HSV NUCLEOTIDYL TRANSFERASES AND USES THEREFOR | SAINT LOUIS UNIVERSITY (US) | 2015-05-28 | — | — | WO | disclosed |