Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 6/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10006447 | 1.00 | FFAR2 (0.37) | FFAR2CNR1P2RX3CNR2AAK1 | |
| SCHEMBL10006261 | 0.96 | AAK1 (0.33) | FFAR2CNR1P2RX3AAK1APP | |
| SCHEMBL10006480 | 0.95 | AAK1 (0.34) | FFAR2CNR1AAK1 | |
| SCHEMBL11932122 | 0.93 | AAK1 (0.33) | AAK1 | |
| SCHEMBL10006603 | 0.93 | AAK1 (0.33) | AAK1 | |
| SCHEMBL9899687 | 0.93 | TRPV1 (0.36) | FFAR2CNR1HTRA1 | |
| SCHEMBL10006450 | 0.93 | TRPV1 (0.36) | FFAR2CNR1HTRA1 | |
| SCHEMBL10006232 | 0.92 | TRPV1 (0.36) | AAK1 | |
| SCHEMBL10006429 | 0.92 | CYP1A2 (0.38) | FFAR2CNR1CNR2HTRA1 | |
| SCHEMBL10006844 | 0.92 | AAK1 (0.33) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649045-B1 | SUBSTITUTED 1-BENZYLCYCLOALKYLCARBOXLIC ACIDS AND USE THEREOF | BAYER IP GMBH (DE) | 2015-05-27 | — | — | EP | disclosed |