⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678467 | 0.80 | — | — | |
| SCHEMBL8065366 | 0.77 | — | — | |
| SCHEMBL8065365 | 0.77 | — | — | |
| SCHEMBL10818055 | 0.76 | — | — | |
| SCHEMBL10818043 | 0.76 | — | — | |
| SCHEMBL28605204 | 0.76 | — | — | |
| SCHEMBL28072502 | 0.75 | GABRR1 (0.31) | — | |
| SCHEMBL24701866 | 0.72 | — | — | |
| SCHEMBL12968965 | 0.72 | — | — | |
| SCHEMBL15354429 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110082075-A1 | Anti-viral fusion peptides | PRENDERGAST KENNETH FRANCIS | 2011-04-07 | — | — | US | disclosed |
| US-7585508-B1 | Fusion proteins comprising CD4 and the malaria parasite merozoite glycophorin binding protein 130 (GBP-130) | PRENDERGAST KENNETH F | 2009-09-08 | — | — | US | disclosed |
| EP-0630407-B1 | ANTI-VIRAL FUSION PEPTIDES | PRENDERGAST KENNETH FRANCIS (GB) | 2000-08-02 | — | — | EP | disclosed |
| EP-0716703-A1 | GLYCOPHORIN BINDING PROTEIN (GBP130) FUSION COMPOSITIONS | PRENDERGAST, Kenneth, Francis (GB) | 1996-06-19 | — | — | EP | disclosed |
| WO-1995006737-A1 | GLYCOPHORIN BINDING PROTEIN (GBP130) FUSION COMPOSITIONS | PRENDERGAST KENNETH FRANCIS (GB) | 1995-03-09 | — | — | WO | disclosed |
| EP-0630407-A1 | ANTI-VIRAL FUSION PEPTIDES | PRENDERGAST, Kenneth, Francis (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018160-A1 | ANTI-VIRAL FUSION PEPTIDES | PRENDERGAST KENNETH FRANCIS (GB) | 1993-09-16 | — | — | WO | disclosed |