Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397488 | 0.83 | GLRA1 (0.35) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL11340090 | 0.75 | GABRR1 (0.31) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL1674927 | 0.75 | — | — | |
| SCHEMBL9434734 | 0.74 | TSHR (0.43) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL28103576 | 0.74 | LMNA (0.31) | LMNA | |
| SCHEMBL9434744 | 0.74 | TSHR (0.43) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL9227811 | 0.74 | MAPT (0.37) | LMNANPSR1 | |
| SCHEMBL7628488 | 0.73 | — | — | |
| SCHEMBL489998 | 0.71 | — | — | |
| SCHEMBL11233473 | 0.71 | CRBN (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105823829-A | Detection method of N-(1-oxo-4-hydroxy-2-butenyl)aminoacetamide | 哈尔滨三联药业股份有限公司 | 2016-08-03 | — | — | CN | claimed |
| CN-105820062-A | N-(1-oxo-4-hydroxy-2-butenyl)aminoacetamide compound and preparation method and application thereof | 哈尔滨三联药业股份有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-105823829-A | Detection method of N-(1-oxo-4-hydroxy-2-butenyl)aminoacetamide | 哈尔滨三联药业股份有限公司 | 2016-08-03 | — | — | CN | disclosed |