SCHEMBL16751966

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16751977	0.84	AKR1C3 (0.43)	MAPK1AKR1C3AKR1C2FFAR2PSEN1
	SCHEMBL16751910	0.81	ALDH1A1 (0.40)	ALDH1A1AKR1C3AKR1C2FFAR2PSEN1
	SCHEMBL30008055	0.78	MAPK1 (0.41)	MAPK1SMN1; SMN2FFAR2PSEN1PSEN2
	SCHEMBL16751962	0.76	HCAR2 (0.42)	MAPK1AKR1C3AKR1C2FFAR2
	SCHEMBL16751892	0.76	AKR1C3 (0.49)	ALDH1A1MAPK1AKR1C3AKR1C2P4HTM
	SCHEMBL8357926	0.74	ESR1 (0.39)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL12302670	0.73	MEN1 (0.41)	ALDH1A1MAPK1SMN1; SMN2
	SCHEMBL1062369	0.72	AKR1C3 (0.51)	AKR1C3AKR1C2
	SCHEMBL16751967	0.72	AKR1C3 (0.50)	AKR1C3AKR1C2FFAR2PSEN1PSEN2
	SCHEMBL9807335	0.71	ESR1 (0.41)	AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.