Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.89 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.61 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PEPD | P12955 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5427711 | 0.94 | KIF11 (1.00) | KIF11EPHX2ALDH1A1PTGS1 | |
| SCHEMBL30772270 | 0.87 | KIF11 (0.70) | KIF11EPHX2ALDH1A1PTGS1TGM2 | |
| SCHEMBL29145261 | 0.84 | KIF11 (0.66) | KIF11EPHX2PTGS1TGM2NPC1 | |
| SCHEMBL28233684 | 0.84 | KIF11 (0.66) | KIF11EPHX2ALDH1A1NPC1PEPD | |
| SCHEMBL28729179 | 0.83 | EPHX2 (1.00) | KIF11EPHX2TGM2NPC1RAB9A | |
| SCHEMBL11003408 | 0.83 | EPHX2 (1.00) | KIF11EPHX2TGM2NPC1RAB9A | |
| SCHEMBL2518624 | 0.83 | EPHX2 (0.76) | KIF11EPHX2ALDH1A1PTGS1TGM2 | |
| SCHEMBL11626027 | 0.82 | SMN1; SMN2 (0.69) | KIF11EPHX2ALDH1A1NPC1PEPD | |
| SCHEMBL4099319 | 0.82 | KIF11 (0.63) | KIF11EPHX2ALDH1A1PTGS1TGM2 | |
| SCHEMBL5062623 | 0.82 | PEPD (0.80) | KIF11ALDH1A1NPC1RAB9APEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022036063-A2 | COMPOSITIONS AND METHODS FOR TREATING PROLIFERATIVE DISEASES | THE BROAD INSTITUTE, INC. (US) | 2022-02-17 | — | — | WO | claimed |
| CN-111988996-A | Increasing yield of nut bearing plants | UPL有限责任公司 | 2020-11-24 | — | — | CN | claimed |
| US-20190254281-A1 | ENHANCED YIELD IN NUT BEARING PLANTS | UPL CORPORATION LTD. (MU) | 2019-08-22 | — | — | US | claimed |
| WO-2019161274-A1 | ENHANCED YIELD IN NUT BEARING PLANTS | UPL CORPORATION LTD. (MU) | 2019-08-22 | — | — | WO | claimed |
| CN-109476637-A | heterocyclic Prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2019-03-15 | — | — | CN | claimed |
| CN-106496116-A | Quinolines containing double aryl urea structures and application thereof | 沈阳药科大学 | 2017-03-15 | — | — | CN | claimed |
| CN-103221388-A | Novel sulfonamide compounds for inhibition of metastatic tumor growth | METASIGNAL THERAPEUTICS INC | 2013-07-24 | — | — | CN | claimed |
| EP-2611806-A1 | DEUTERIUM-ENRICHED HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Ascepion Pharmaceuticals, Inc. (CN) | 2013-07-10 | — | — | EP | claimed |
| WO-2012028106-A1 | DEUTERIUM-ENRICHED HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ASCEPION PHARMACEUTICALS, INC. (CN) | 2012-03-08 | — | — | WO | claimed |
| EP-1891072-A2 | SUBSTITUTED 7, 8-DIHYDRO-1H-PYRIMIDO[4,5-B][1,4] DIAZEPIN-4-AMINES AS KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2008-02-27 | — | — | EP | claimed |
| WO-2006124813-A2 | SUBSTITUTED 7, 8-DIHYDRO-1H-PYRIMIDO [4,5-B] [1,4] DIAZEPIN-4-AMINES AS?KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2006-11-23 | — | — | WO | claimed |
| CN-1492762-A | Azoles as malonyl-COA decarboxylase inhibitors useful as metabolic modulators | ������ҩ��ʽ���� | 2004-04-28 | — | — | CN | claimed |
| EP-1370260-A2 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-12-17 | — | — | EP | claimed |
| WO-2002068586-A2 | HIV/FIV PROTEASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-09-06 | — | — | WO | claimed |
| WO-2002066035-A2 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-08-29 | — | — | WO | claimed |
| WO-2001064036-A1 | ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2001-09-07 | — | — | WO | claimed |
| US-6242385-B1 | SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. | 2001-06-05 | — | — | US | claimed |
| EP-1005459-A1 | SUBSTITUTED ISOQUINOLINES AS ANTICONVULSIVANTS | SMITHKLINE BEECHAM PLC (GB) | 2000-06-07 | — | — | EP | claimed |
| WO-1999014197-A1 | SUBSTITUTED ISOQUINOLINES AS ANTICONVULSIVANTS | SMITHKLINE BEECHAM PLC (GB) | 1999-03-25 | — | — | WO | claimed |
| US-4250319-A | RIPENER FOR SUGARCANE | W. R. GRACE & CO. (US) | 1981-02-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190254281-A1 | ENHANCED YIELD IN NUT BEARING PLANTS | NUTF2, MYCBP, MYCBP2 | KIF11 2646/4885EPHX2 1807/4885ALDH1A1 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.