SCHEMBL16757624

SCHEMBL16757624

CC(C)(C)OC(=O)CC[C@H](N)C(=O)NCCOCCOCCNC(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ GAA P10253 1/20 0.43
▸ PLK1 P53350 2/20 0.42
▸ TDP1 Q9NUW8 1/20 0.38
▸ CA2 P00918 5/20 0.38
▸ CA12 O43570 4/20 0.38
▸ CA1 P00915 4/20 0.38
▸ CA9 Q16790 4/20 0.38
▸ MAOA P21397 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ ADRB2 P07550 1/20 0.36
▸ HTR1A P08908 1/20 0.36
▸ TLR2 O60603 2/20 0.36
▸ EPHX1 P07099 1/20 0.36
▸ DPP7 Q9UHL4 1/20 0.35
▸ BCHE P06276 1/20 0.35
▸ CNR2 P34972 1/20 0.35
▸ IDO1 P14902 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16757623 1.00 MEN1 (0.43) MEN1KMT2AGAAPLK1TDP1
SCHEMBL31756841 0.90 PLK1 (0.42) MEN1KMT2APLK1CA2TLR2
SCHEMBL26232048 0.90 PLK1 (0.42) MEN1KMT2APLK1CA2TLR2
SCHEMBL16791114 0.90 PLK1 (0.42) MEN1KMT2APLK1CA2TLR2
SCHEMBL29131983 0.90 PLK1 (0.42) MEN1KMT2APLK1CA2TLR2
SCHEMBL23417972 0.90 TLR2 (0.44) MEN1KMT2APLK1CA2TLR2
SCHEMBL16757612 0.89 TLR2 (0.45) MEN1KMT2AGAAPLK1CA2
SCHEMBL21836141 0.89 TLR2 (0.45) MEN1KMT2AGAAPLK1CA2
SCHEMBL25132967 0.86 PLK1 (0.42) MEN1KMT2AGAAPLK1TDP1
SCHEMBL19732528 0.85 TDP1 (0.48) MEN1KMT2AGAATDP1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4592275-A2 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2025-07-30 — — EP disclosed
EP-3074010-B1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE INC (US) 2025-05-14 — — EP disclosed
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2025-02-04 — — US disclosed
US-20220153696-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2022-05-19 — — US disclosed
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2021-11-23 — — US disclosed
US-20200317610-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2020-10-08 — — US disclosed
US-10604483-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2020-03-31 — — US disclosed
US-10464894-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCES, INC. (US) 2019-11-05 — — US disclosed
US-20170049907-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE CATALENT PHARMA SOLUTIONS, LLC 2017-02-23 — — US disclosed
US-9493413-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2016-11-15 — — US disclosed
EP-3074010-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2016-10-05 — — EP disclosed
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE R.P. SCHERER TECHNOLOGIES, LLC 2015-06-11 — — US disclosed
WO-2015081282-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE, INC. (US) 2015-06-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE DNPEP, QPCT, PDS5A MEN1 903/4885KMT2A 1630/4885GAA 1772/4885
US-20220153696-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate DNPEP, QPCT, PDS5A MEN1 903/4885KMT2A 1630/4885GAA 1772/4885
US-20170049907-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE DNPEP, QPCT, PDS5A MEN1 903/4885KMT2A 1630/4885GAA 1772/4885
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A MEN1 903/4885KMT2A 1630/4885GAA 1772/4885
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A MEN1 903/4885KMT2A 1630/4885GAA 1772/4885
US-10464894-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A MEN1 903/4885KMT2A 1630/4885GAA 1772/4885
US-10604483-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A MEN1 903/4885KMT2A 1630/4885GAA 1772/4885
US-20200317610-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate DNPEP, QPCT, PDS5A MEN1 903/4885KMT2A 1630/4885GAA 1772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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