Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 12/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31756841 | 0.90 | PLK1 (0.42) | PLK1MEN1KMT2ADPP7TLR2 | |
| SCHEMBL29131983 | 0.90 | PLK1 (0.42) | PLK1MEN1KMT2ADPP7TLR2 | |
| SCHEMBL26232048 | 0.90 | PLK1 (0.42) | PLK1MEN1KMT2ADPP7TLR2 | |
| SCHEMBL16757624 | 0.90 | MEN1 (0.43) | PLK1MEN1KMT2ADPP7TLR2 | |
| SCHEMBL16757623 | 0.90 | MEN1 (0.43) | PLK1MEN1KMT2ADPP7TLR2 | |
| SCHEMBL23417972 | 0.90 | TLR2 (0.44) | PLK1MEN1KMT2ADPP7TLR2 | |
| SCHEMBL16757612 | 0.89 | TLR2 (0.45) | PLK1MEN1KMT2ADPP7TLR2 | |
| SCHEMBL21836141 | 0.89 | TLR2 (0.45) | PLK1MEN1KMT2ADPP7TLR2 | |
| SCHEMBL19506154 | 0.88 | CTSS (0.37) | PLK1DPP7TLR2 | |
| SCHEMBL23463183 | 0.88 | PLK1 (0.40) | PLK1MEN1KMT2ADPP7TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170049907-A1 | HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE | CATALENT PHARMA SOLUTIONS, LLC | 2017-02-23 | — | — | US | disclosed |
| US-9493413-B2 | Hydrazinyl-pyrrolo compounds and methods for producing a conjugate | REDWOOD BIOSCIENCE, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| US-20150352225-A1 | Anti-Her2 Antibody-Maytansine Conjugates and Methods of Use Thereof | R.P. SCHERER TECHNOLOGIES, INC. | 2015-12-10 | — | — | US | disclosed |
| US-20150157736-A1 | HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE | R.P. SCHERER TECHNOLOGIES, LLC | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150157736-A1 | HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE | DNPEP, QPCT, PDS5A | PLK1 304/4885MEN1 903/4885KMT2A 1630/4885 |
| US-20170049907-A1 | HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE | DNPEP, QPCT, PDS5A | PLK1 304/4885MEN1 903/4885KMT2A 1630/4885 |
| US-20150352225-A1 | Anti-Her2 Antibody-Maytansine Conjugates and Methods of Use Thereof | ERBB2, EGFR, ERBB3 | PLK1 665/4885MEN1 2819/4885KMT2A 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.