Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15788490 | 0.81 | CYP4F2 (0.52) | TSHRCYP4F2CYP4A11RAB9APOLB | |
| SCHEMBL34953 | 0.80 | TSHR (0.70) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| SCHEMBL14740775 | 0.79 | CA12 (0.50) | TSHRPOLBTP53ALDH1A1CYP1A2 | |
| SCHEMBL15985232 | 0.79 | ACHE (0.47) | RAB9ATP53ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL29966404 | 0.78 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| Methyl Alcohol SCHEMBL28469619 | 0.78 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| Potassium SCHEMBL30190417 | 0.78 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| SCHEMBL10941453 | 0.78 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| SCHEMBL9943503 | 0.78 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| Ammonia Solution, Strong SCHEMBL28556515 | 0.78 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015081280-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |
| WO-2015081280-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |