Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 7/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864192 | 0.79 | F10 (0.69) | F10 | |
| SCHEMBL28755710 | 0.72 | F10 (0.68) | F10 | |
| SCHEMBL6508642 | 0.71 | F10 (0.60) | F10 | |
| SCHEMBL4912657 | 0.71 | F10 (0.49) | F10 | |
| SCHEMBL12754754 | 0.70 | TDP1 (0.52) | F10 | |
| SCHEMBL4922159 | 0.70 | F10 (0.54) | F10 | |
| SCHEMBL1481964 | 0.70 | TDP1 (0.52) | F10 | |
| SCHEMBL1479455 | 0.69 | TDP1 (0.44) | F10 | |
| SCHEMBL3866213 | 0.69 | F10 (0.67) | F10 | |
| SCHEMBL1480143 | 0.69 | F10 (0.45) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4668614-B2 | — | — | 2011-04-13 | — | — | JP | claimed |
| JP-2006500369-A | — | — | 2006-01-05 | — | — | JP | claimed |
| EP-1558247-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 2005-08-03 | — | — | EP | claimed |
| WO-2004017963-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-03-04 | — | — | WO | claimed |