SCHEMBL1675967

SCHEMBL1675967

NC(=O)CCCCc1ccc(N2CCOCC2=O)c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 10/20 0.42
NAAA Q02083 5/20 0.40
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1377031 0.93 F10 (0.43) F10NPC1
SCHEMBL1377241 0.87 F10 (0.44) F10NAAA
SCHEMBL1675780 0.81 F10 (0.48) F10NAAA
SCHEMBL1379921 0.81 F10 (0.49) F10
SCHEMBL1379762 0.80 F10 (0.47) F10
SCHEMBL77406 0.75 MAPT (0.43) F10NPC1
SCHEMBL1675832 0.73 F10 (0.50) F10
SCHEMBL1482047 0.73 HPGD (0.49) F10NPC1
SCHEMBL1675756 0.72 F10 (0.46) F10
SCHEMBL8306339 0.72 ALDH1A1 (0.45) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4668614-B2 2011-04-13 JP claimed