Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16760579 | 1.00 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2896443 | 0.83 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2886197 | 0.83 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2886194 | 0.83 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL18832132 | 0.82 | GAA (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL16759881 | 0.82 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL22971403 | 0.82 | CYP1A2 (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL16759680 | 0.82 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL16759683 | 0.82 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1396422 | 0.81 | MGAM (0.42) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617252-B2 | Processes for preparing dihydropyrimidine derivatives and intermediates thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-04-11 | — | — | US | disclosed |
| EP-3074393-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2016-10-05 | — | — | EP | disclosed |
| US-20160264562-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-09-15 | — | — | US | disclosed |
| WO-2015078391-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264562-A1 | PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF | DPYD, DHPS, DHODH | MGAM 2386/4885GAA 819/4885SI 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.