Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30237979 | 0.85 | CA1 (0.44) | LPLLIPGALDH1A1TP53MAPK1 | |
| SCHEMBL2774133 | 0.85 | CA1 (0.44) | LPLLIPGALDH1A1TP53MAPK1 | |
| SCHEMBL121468 | 0.82 | LPL (0.54) | LPLLIPGCTNNB1WNT3AMAPK1 | |
| SCHEMBL15280673 | 0.77 | LPL (0.40) | LPLLIPGCA12CA1CA2 | |
| SCHEMBL22131084 | 0.73 | LPL (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL24254043 | 0.73 | APP (0.41) | LPLLIPGCYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL28329737 | 0.72 | CA1 (0.35) | LPLLIPGALDH1A1MAPTTP53 | |
| SCHEMBL28147238 | 0.72 | EGFR (0.39) | LPLLIPGCYP3A4ALDH1A1MAPT | |
| SCHEMBL1870652 | 0.71 | JAK2 (0.38) | LPLLIPGCYP3A4ALDH1A1MAPT | |
| SCHEMBL1642097 | 0.70 | EGFR (0.45) | LPLLIPGCYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881398-A1 | Method for preparing aminoarylborane compounds or derivatives thereof | Université de Bordeaux I (FR) | 2015-06-10 | — | — | EP | disclosed |