Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 12/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676302 | 1.00 | KDM4E (0.38) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL1676017 | 0.89 | KDM4E (0.38) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL1676015 | 0.89 | KDM4E (0.38) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL1676383 | 0.86 | KDM4E (0.45) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL1676385 | 0.86 | KDM4E (0.45) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL1483163 | 0.84 | KDM4E (0.42) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL1483160 | 0.84 | KDM4E (0.42) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL1676407 | 0.84 | ACLY (0.41) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL1676404 | 0.84 | ACLY (0.41) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL1481660 | 0.83 | KDM4E (0.43) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092553-A1 | Substituted Azole Derivatives, Compositions, and Methods of Use | TRANSTECH PHARMA, INC. (US) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092553-A1 | Substituted Azole Derivatives, Compositions, and Methods of Use | PTPRO, PTPN5, PTPRE | KDM4E 733/4885SMN1; SMN2 4417/4885NPC1 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.