Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 6/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | PIK3C2B | O00750 | 4/20 | 0.32 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012953 | 0.87 | AOC3 (0.36) | HTR2CSLC6A4AOC3USP30NAPEPLD | |
| SCHEMBL503809 | 0.85 | AOC3 (0.35) | NPY1RAOC3MAPKAPK2TGFBR1BRD9 | |
| SCHEMBL960988 | 0.84 | HTR2C (0.34) | HTR2CSLC6A4USP30TGFBR1GPR119 | |
| SCHEMBL7016912 | 0.83 | HTR2C (0.35) | HTR2CSLC6A4AOC3USP30GPR119 | |
| SCHEMBL7015313 | 0.80 | PIK3C2B (0.34) | HTR2CSLC6A4PIK3C2BNAPEPLD | |
| SCHEMBL959862 | 0.79 | HTR2C (0.34) | HTR2CSLC6A4 | |
| SCHEMBL7015714 | 0.77 | USP30 (0.34) | HTR2CSLC6A4USP30TGFBR1PIK3C2B | |
| SCHEMBL962329 | 0.77 | HTR2C (0.33) | HTR2CSLC6A4 | |
| SCHEMBL504009 | 0.77 | NPY1R (0.45) | NPY1RAOC3USP30MAPKAPK2 | |
| SCHEMBL7012036 | 0.76 | ZAP70 (0.32) | HTR2CSLC6A4PIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424860-A1 | HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE | MSD K.K. (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120028970-A1 | HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE | MSD K.K. (JP) | 2012-02-02 | — | — | US | disclosed |
| WO-2010126163-A1 | HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028970-A1 | HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE | AR, NR5A1, ARL1 | HTR2C 1011/4885SLC6A4 2369/4885NPY1R 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.