Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016912 | 0.89 | HTR2C (0.35) | AOC3USP30NAPEPLDHTR2CSLC6A4 | |
| SCHEMBL167647 | 0.87 | HTR2C (0.35) | AOC3USP30NAPEPLDHTR2CSLC6A4 | |
| SCHEMBL7015313 | 0.83 | PIK3C2B (0.34) | NAPEPLDHTR2CSLC6A4SLC16A3SLC16A1 | |
| SCHEMBL960988 | 0.83 | HTR2C (0.34) | USP30NAPEPLDCETPHTR2CSLC6A4 | |
| SCHEMBL7015714 | 0.83 | USP30 (0.34) | USP30HTR2CSLC6A4LGMNLNPEP | |
| SCHEMBL7018655 | 0.83 | AOC3 (0.36) | AOC3USP30NAPEPLDCETPAGXT | |
| SCHEMBL7018651 | 0.82 | AOC3 (0.35) | AOC3USP30NAPEPLDCETPAGXT | |
| SCHEMBL7018069 | 0.79 | HTR2C (0.31) | HTR2CSLC6A4 | |
| SCHEMBL959862 | 0.78 | HTR2C (0.34) | HTR2CSLC6A4 | |
| SCHEMBL7017580 | 0.77 | NPY1R (0.37) | HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |