Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4109450 | 1.00 | S1PR3 (0.54) | S1PR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4109455 | 1.00 | S1PR3 (0.54) | S1PR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4118759 | 0.94 | MAPT (0.54) | S1PR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4123454 | 0.94 | S1PR3 (0.49) | S1PR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4118763 | 0.94 | MAPT (0.54) | S1PR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4123456 | 0.94 | S1PR3 (0.49) | S1PR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4102773 | 0.93 | S1PR3 (0.48) | S1PR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4102776 | 0.93 | S1PR3 (0.48) | S1PR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4112762 | 0.93 | S1PR3 (0.48) | S1PR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4108040 | 0.93 | S1PR3 (0.48) | S1PR3MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723801-B9 | TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR | BIORA THERAPEUTICS INC (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3723801-B1 | TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR | BIORA THERAPEUTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20220135666-A1 | TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR | GLAS USA LLC | 2022-05-05 | — | — | US | disclosed |
| US-20210204539-A1 | Method for Suppressing Freezing Damage and Composition for Preventing Freezing Damage | KYOTO UNIVERSITY (JP) | 2021-07-08 | — | — | US | disclosed |
| EP-3808176-A1 | METHOD FOR SUPPRESSING FREEZING DAMAGE AND COMPOSITION FOR PREVENTING FREEZING DAMAGE | Kyoto University (JP) | 2021-04-21 | — | — | EP | disclosed |
| US-20190117596-A1 | TY-52156 COMPOUNDS FOR THE TREATMENT OF CANCER | WAYNE STATE UNIVERSITY (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2017190077-A1 | TY-52156 COMPOUNDS FOR THE TREATMENT OF CANCER | WAYNE STATE UNIVERSITY (US) | 2017-11-02 | — | — | WO | disclosed |
| US-20150157584-A1 | INHIBITORS OF HIPPO-YAP SIGNALING PATHWAY | THE J. DAVID GLADSTONE INSTITUTES (US) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117596-A1 | TY-52156 COMPOUNDS FOR THE TREATMENT OF CANCER | S1PR3, S1PR1, S1PR4 | S1PR3 1/4885MEN1 1023/4885KMT2A 865/4885 |
| US-20150157584-A1 | INHIBITORS OF HIPPO-YAP SIGNALING PATHWAY | YAP1, MST1, YES1 | S1PR3 2662/4885MEN1 3506/4885KMT2A 2380/4885 |
| US-20220135666-A1 | TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR | S1PR2, S1PR1, S1PR4 | S1PR3 5/4885MEN1 306/4885KMT2A 2761/4885 |
| US-20210204539-A1 | Method for Suppressing Freezing Damage and Composition for Preventing Freezing Damage | SPHK1, S1PR1, SPHK2 | S1PR3 6/4885MEN1 1393/4885KMT2A 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.