SCHEMBL16766356

SCHEMBL16766356

C=CC1(O)CCCC1CCCCCC

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
EPHX1 P07099 1/20 0.33
ALDH1A1 P00352 1/20 0.32
S1PR1 P21453 2/20 0.31
S1PR3 Q99500 2/20 0.31
GBA1 P04062 1/20 0.31
S1PR2 O95136 1/20 0.31
S1PR4 O95977 1/20 0.31
S1PR5 Q9H228 1/20 0.31
TSHR P16473 1/20 0.31
LTB4R Q15722 2/20 0.30
LTB4R2 Q9NPC1 2/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH4 P08319 1/20 0.30
LSS P48449 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16766223 0.98 TDP1 (0.37) TDP1EPHX1
SCHEMBL16766688 0.93 TDP1 (0.41) TDP1
SCHEMBL16765819 0.86 CA1 (0.31) TDP1
SCHEMBL16767009 0.79 CDC25A (0.37) TDP1
SCHEMBL16765710 0.76 TDP1 (0.40) TDP1EPHX1ALDH1A1S1PR1S1PR3
SCHEMBL16765708 0.76 TDP1 (0.40) TDP1EPHX1ALDH1A1S1PR1S1PR3
SCHEMBL16766122 0.75 MEN1 (0.32) ALDH1A1TSHR
SCHEMBL16766047 0.75 CDC25A (0.33)
SCHEMBL16766423 0.75 TDP1 (0.39) TDP1EPHX1ALDH1A1S1PR1S1PR3
SCHEMBL16766402 0.75 TDP1 (0.39) TDP1EPHX1ALDH1A1S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104710283-B Cyclopentanol compound 国际香料和香精公司 2019-06-11 CN disclosed
US-9701925-B2 Cyclopentanol compounds INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2017-07-11 US disclosed
US-20160160152-A1 NOVEL CYCLOPENTANOL COMPOUNDS INTERNATIONAL FLAVORS & FRAGRANCES INC. 2016-06-09 US disclosed
US-9290718-B2 Cyclopentanol compounds INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2016-03-22 US disclosed
EP-2902468-A2 Novel cyclopentanol compounds International Flavors & Fragrances Inc. (US) 2015-08-05 EP disclosed
CN-104710283-A Novel cyclopentanol compounds INT FLAVORS & FRAGRANCES INC 2015-06-17 CN disclosed
US-20150159118-A1 NOVEL CYCLOPENTANOL COMPOUNDS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2015-06-11 US disclosed