SCHEMBL1676683

SCHEMBL1676683

CC[C@H](C)[C@@H]([C]=O)NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6852866 1.00
SCHEMBL1676681 1.00
SCHEMBL9100792 1.00
SCHEMBL6852863 1.00
SCHEMBL5312610 1.00
SCHEMBL6244444 0.75 ALDH1A1 (0.39)
SCHEMBL7610492 0.73 ALDH1A1 (0.34)
SCHEMBL1657591 0.73 ALDH1A1 (0.36)
SCHEMBL4957734 0.73 ALDH1A1 (0.36)
SCHEMBL1657594 0.73 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130046077-A1 DOLASTATIN 15 DERIVATIVES ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2013-02-21 US claimed
US-8163698-B2 Dolastatin 15 derivatives ABBOTT GMBH & CO. KG (DE) 2012-04-24 US claimed
JP-4508413-B2 2010-07-21 JP claimed
US-20100099843-A1 DOLASTATIN 15 DERIVATIVES ABBOTT GMBH & CO. KG (DE) 2010-04-22 US claimed
US-7662786-B2 oligopeptides; anticarcinogenic agent; good water solubility and cost effective; , B, D, E, F, G and K are alpha -amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as,an amino group, an N-substituted amino group, a beta -hydroxylamino group, an alkoxy group ABBOTT GMBH & CO. KG (DE) 2010-02-16 US claimed
EP-1451209-A4 TETRA-,PENTA-,HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LAB (US) 2009-06-03 EP claimed
EP-1450840-A4 DI-, TRI,- AND TETRA-PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LAB (US) 2009-06-03 EP claimed
US-20080071062-A1 TETRA-, PENTA-, HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY HAVIV FORTUNA 2008-03-20 US claimed
EP-1461356-A4 HEXA-, HEPTA-, AND OCTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LAB (US) 2007-12-12 EP claimed
US-20070167376-A1 Hexa-, Hepta-, and Octapeptides Having Antiangiogenic Activity HAVIV FORTUNA 2007-07-19 US claimed
US-20010009901-A1 Antineoplastic peptides BASF AKTIENGESELLSCHAFT GERMANY 2001-07-26 US claimed
WO-2001038397-A1 N-ALKYLATED PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LABORATORIES (US) 2001-05-31 WO claimed
US-6143721-A FOR TREATING CANCER IN MAMMALS BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US claimed
EP-0991658-A1 DOLASTATIN 15 DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2000-04-12 EP claimed
WO-1999003879-A1 DOLASTATIN 15 DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1999-01-28 WO claimed
EP-0866800-A2 ANTINEOPLASTIC PEPTIDES BASF AKTIENGESELLSCHAFT (DE) 1998-09-30 EP claimed
WO-1997022621-A2 ANTINEOPLASTIC PEPTIDES BASF AKTIENGESELLSCHAFT (DE) 1997-06-26 WO claimed
EP-0296122-B1 CYCLOSPORINS AND THEIR USE AS PHARMACEUTICALS SANDOZ AG (CH) 1993-09-29 EP claimed
US-5182264-A Angiotensin II receptor blockers as antiglaucoma agents SCHERING CORPORATION (US) 1993-01-26 US claimed
EP-0296122-A2 Cyclosporins and their use as pharmaceuticals SANDOZ AG (CH) 1988-12-21 EP claimed