SCHEMBL1676774

SCHEMBL1676774

CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(=O)NC(CCC(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.51
POLB P06746 1/20 0.46
NOD1 Q9Y239 5/20 0.43
PLA2G2C Q5R387 1/20 0.43
PLA2G10 O15496 1/20 0.40
HDAC8 Q9BY41 1/20 0.39
FOLH1 Q04609 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20450604 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10
SCHEMBL12674184 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10
SCHEMBL20450548 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10
SCHEMBL25445243 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10
SCHEMBL20450549 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10
SCHEMBL24817622 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10
SCHEMBL17747011 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10
SCHEMBL16538711 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10
SCHEMBL22074686 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10
SCHEMBL20450601 1.00 KMT2A (0.51) KMT2APOLBNOD1PLA2G2CPLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024134676-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE DR. REDDY’S LABORATORIES LIMITED (IN) 2024-06-27 WO disclosed
US-9150633-B2 Insulin analogues with an acyl and alkylene glycol moiety NOVO NORDISK A/S (DK) 2015-10-06 US disclosed
EP-2178912-B1 INSULIN ANALOGUES WITH AN ACYL AND AKLYLENE GLYCOL MOIETY NOVO NORDISK AS (DK) 2015-07-08 EP disclosed
EP-2708554-A1 Insulin analogues with an acyl and alkylene glycol moiety NOVO NORDISK A/S (DK) 2014-03-19 EP disclosed
US-20110098440-A1 Insulin Analogues with an Acyl and Alkylene Glycol Moiety NOVO NORDISK A/S (DK) 2011-04-28 US disclosed
EP-2178912-A1 INSULIN ANALOGUES WITH AN ACYL AND AKLYLENE GLYCOL MOIETY Novo Nordisk A/S (DK) 2010-04-28 EP disclosed
WO-2009022013-A1 INSULIN ANALOGUES WITH AN ACYL AND AKLYLENE GLYCOL MOIETY NOVO NORDISK A/S (DK) 2009-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098440-A1 Insulin Analogues with an Acyl and Alkylene Glycol Moiety IAPP, INSR, IGF1R KMT2A 418/4885POLB 3744/4885NOD1 3208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.