Edetic Acid

Edetic Acid

SCHEMBL167680

NC(CC(=O)O)(CC(=O)O)C(N)(CC(=O)O)CC(=O)O.O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.64
EYA2 O00167 1/20 0.64
APP P05067 1/20 0.64
ACE P12821 1/20 0.64
BLM P54132 2/20 0.61
PMP22 Q01453 2/20 0.61
KDM4E B2RXH2 1/20 0.61
LMNA P02545 1/20 0.61
CHRM2 P08172 1/20 0.61
ADRA2A P08913 1/20 0.61
ALOX15 P16050 1/20 0.61
TSHR P16473 1/20 0.61
DRD1 P21728 1/20 0.61
SLC6A2 P23975 1/20 0.61
SLC6A4 P31645 1/20 0.61
CYP2C19 P33261 1/20 0.61
ADRA1A P35348 1/20 0.61
DRD3 P35462 1/20 0.61
SLC6A3 Q01959 1/20 0.61
HRH3 Q9Y5N1 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetic Acid SCHEMBL8371874 0.98 TDP1 (0.61) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL5073273 0.92 TDP1 (0.54) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL21113636 0.89 TDP1 (0.50) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL6284520 0.89 TDP1 (0.50) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL476467 0.86 TDP1 (0.52) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL6142172 0.86 TDP1 (0.47) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL138172 0.81 TDP1 (0.56) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL1976384 0.80 TDP1 (0.88) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL16714076 0.80 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL8607480 0.80 TDP1 (1.00) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11337989-B2 Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound EVOFEM, INC. (US) 2022-05-24 US claimed
EP-3735966-A1 COMPOSITIONS AND METHODS FOR INHIBITING INFLAMMATION AND DISEASES USING AN ALGINIC ACID-BASED ANTIMICROBIAL COMPOUND Evofem, Inc. (US) 2020-11-11 EP claimed
EP-3128992-B1 ORAL CARE COMPOSITIONS BASF SE (DE) 2019-11-20 EP claimed
EP-3308771-A1 COMPOSITIONS AND METHODS FOR ENHANCING THE EFFICACY OF CONTRACEPTIVE MICROBICIDES Evofem, Inc. (US) 2018-04-18 EP claimed
WO-2015070072-A1 METHODS FOR MANUFACTURING CONTRACEPTIVE MICROBICIDES WITH ANTIVIRAL PROPERTIES EVOFEM, INC. (US) 2015-05-14 WO claimed
WO-2009043588-A2 PH REGULATING ANTIBACTERIAL FILMS FOR THE ORAL OR VAGINAL CAVITY LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH (DE) 2009-04-09 WO claimed
US-20240199648-A1 MAP4K1 INHIBITORS BLUEPRINT MEDICINES CORPORATION 2024-06-20 US disclosed
EP-4380613-A1 HIV-1 VACCINATION AND SAMT-247 MICROBICIDE TO PREVENT HIV-1 INFECTION The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2024-06-12 EP disclosed
US-11992472-B2 Compositions and methods for enhancing the efficacy of contraceptive microbicides EVOFEM, INC. (US) 2024-05-28 US disclosed
EP-3455224-B1 SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF BAYER AG (DE) 2024-03-27 EP disclosed
EP-4305041-A1 MAP4K1 INHIBITORS Blueprint Medicines Corporation (US) 2024-01-17 EP disclosed
WO-2023220645-A1 VACCINE FOR HUMAN T-LYMPHOTROPIC VIRUS-1 THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-11-16 WO disclosed
EP-4244910-A1 CERIUM-ETHYLENEDIAMINE KETONE-TYPE AND CERIUM-SALEN-TYPE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS Credoxys GmbH c/o Institut for Applied Physics (DE) 2023-09-20 EP disclosed
EP-0168342-A1 Process for the preparation of thrombin inhibitors CIBA-GEIGY AG (CH) 1986-01-15 EP disclosed
EP-0160552-A2 Contrast agents for NMR imaging VESTAR, INC. (US) 1985-11-06 EP disclosed
EP-0146785-A1 Process for the preparation of protease inhibitors CIBA-GEIGY AG (CH) 1985-07-03 EP disclosed
EP-0139843-A2 Liquid magnesium-containing formulations HOECHST AKTIENGESELLSCHAFT (DE) 1985-05-08 EP disclosed
EP-0136973-A1 Method and composition for disinfecting water Strausak, Benedikt (CH) 1985-04-10 EP disclosed
US-4469631-A GENETIC ENGINEERING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1984-09-04 US disclosed
US-4350764-A GENETIC ENGINEERING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1982-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199648-A1 MAP4K1 INHIBITORS MAP4K1, MAP4K4, MAP4K2 TDP1 756/4885EYA2 397/4885APP 1117/4885
US-11337989-B2 Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound ALG8, ALG1, EIF2AK2 TDP1 3637/4885EYA2 3705/4885APP 3516/4885
US-11992472-B2 Compositions and methods for enhancing the efficacy of contraceptive microbicides PGF, PGRMC1, PGRMC2 TDP1 1933/4885EYA2 3238/4885APP 4775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.