Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12695590 | 0.90 | POLB (0.49) | — | |
| SCHEMBL12541784 | 0.89 | TTR (0.52) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL22754658 | 0.81 | CHRNA7 (0.51) | — | |
| SCHEMBL16588662 | 0.80 | POLB (0.67) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL12541213 | 0.79 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9ATTR | |
| SCHEMBL12695601 | 0.79 | TYR (0.53) | MEN1KMT2ACYP3A4HTT | |
| SCHEMBL4370405 | 0.78 | CHRNA7 (0.62) | HTTHSP90AB1 | |
| SCHEMBL4724887 | 0.76 | NPC1 (0.60) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL12695587 | 0.75 | RAB9A (0.46) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL12695542 | 0.74 | PTGER1 (0.47) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045405-B2 | Compounds and methods for preparation of diarylpropanes | UNIGEN, INC. (US) | 2015-06-02 | — | — | US | disclosed |