Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1175037 | 0.84 | TDP1 (0.54) | ALDH1A1TSHRKMT2ARAB9AMAPT | |
| SCHEMBL12132589 | 0.84 | CYP2A6 (0.44) | CYP2A6ALDH1A1TSHRKMT2ARAB9A | |
| SCHEMBL25128750 | 0.83 | KMT2A (0.45) | CYP2A6ALDH1A1KMT2ARAB9AMAPT | |
| SCHEMBL15652760 | 0.82 | ERN1 (0.49) | ALDH1A1TSHRKMT2ARAB9ANPC1 | |
| SCHEMBL10415156 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRRAB9ANPC1PKM | |
| SCHEMBL10591550 | 0.82 | CYP2A6 (0.43) | CYP2A6ALDH1A1KMT2ARAB9AMAPT | |
| SCHEMBL11585526 | 0.80 | TYR (0.52) | CYP2A6KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL15920688 | 0.79 | PLK1 (0.47) | TSHRTDP1HTTHPGD | |
| SCHEMBL20844325 | 0.79 | CYP2A6 (0.41) | CYP2A6ALDH1A1KMT2ARAB9AMAPT | |
| SCHEMBL25215149 | 0.79 | HDAC6 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262976-B | Electrochemical synthesis method of benzaldehyde derivative | 国科大杭州高等研究院 | 2024-04-05 | — | — | CN | disclosed |
| CN-116262976-A | Electrochemical synthesis method of benzaldehyde derivative | 国科大杭州高等研究院 | 2023-06-16 | — | — | CN | disclosed |
| WO-2017050922-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-30 | — | — | WO | disclosed |
| CN-102952062-B | Replace benzo-heterocycle compound and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2016-06-08 | — | — | CN | disclosed |
| US-20150152047-A1 | BENZAMIDE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-06-04 | — | — | US | disclosed |
| CN-102952062-A | Substituted benzoheterocyclic compounds and preparation method and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-03-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152047-A1 | BENZAMIDE DERIVATIVE | CYP3A5, HDAC6, BRD1 | CYP2A6 215/4885ALDH1A1 56/4885TSHR 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.