Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 14/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12717115 | 0.87 | FFAR4 (0.72) | CHRM4FFAR4NOTUMCHRM2 | |
| SCHEMBL18825722 | 0.86 | FFAR4 (0.57) | CHRM4FFAR4KCNA5NOTUMCHRM2 | |
| SCHEMBL23502124 | 0.84 | CHRM4 (0.54) | CHRM4FFAR4NOTUMCHRM2 | |
| SCHEMBL2091359 | 0.83 | EPHX2 (0.53) | CHRM4EPHX2NOTUM | |
| SCHEMBL16648937 | 0.83 | POLB (0.67) | CHRM4FFAR4CHRM2 | |
| SCHEMBL16695371 | 0.82 | NOTUM (0.74) | CHRM4FFAR4NOTUM | |
| SCHEMBL1244796 | 0.80 | FFAR4 (0.50) | CHRM4FFAR4KCNA5NOTUMCHRM2 | |
| SCHEMBL435084 | 0.80 | EPHX2 (0.55) | CHRM4FFAR4EPHX2KCNA5CHRM2 | |
| SCHEMBL16769757 | 0.80 | CHRM4 (0.55) | CHRM4EPHX2NOTUMCHRM2 | |
| SCHEMBL16769745 | 0.80 | ACACB (0.53) | CHRM4FFAR4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150575-B2 | Piperidinylpyrazolopyridine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-10-06 | — | — | US | disclosed |
| US-20150152102-A1 | PIPERIDINYLPYRAZOLOPYRIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152102-A1 | PIPERIDINYLPYRAZOLOPYRIDINE DERIVATIVE | LCAT, LPL, LCLAT1 | CHRM4 4550/4885FFAR4 497/4885EPHX2 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.