Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 3/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16967987 | 0.89 | PIP4K2A (0.49) | PIP4K2APRMT5WDR77SRCSLC22A12 | |
| SCHEMBL24753099 | 0.86 | PIP4K2A (0.44) | PIP4K2APRMT5WDR77HCKSRC | |
| SCHEMBL1939828 | 0.86 | PIP4K2A (0.44) | PIP4K2APRMT5WDR77HCKSRC | |
| SCHEMBL12984832 | 0.85 | PRMT5 (0.42) | PIP4K2APRMT5WDR77SLC22A12 | |
| SCHEMBL17877686 | 0.85 | PIP4K2A (0.44) | PIP4K2APRMT5WDR77SRCLCK | |
| SCHEMBL12649114 | 0.82 | PIP4K2A (0.42) | PIP4K2APRMT5WDR77SLC22A12HRH3 | |
| SCHEMBL1442965 | 0.82 | PIP4K2A (0.45) | PIP4K2APRMT5WDR77SRCLCK | |
| SCHEMBL1442966 | 0.82 | PIP4K2A (0.45) | PIP4K2APRMT5WDR77SRCLCK | |
| SCHEMBL12596590 | 0.82 | PIP4K2A (0.42) | PIP4K2APRMT5WDR77HCKSRC | |
| SCHEMBL15636715 | 0.82 | PIP4K2A (0.45) | PIP4K2APRMT5WDR77SRCLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158697-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2017-06-08 | — | — | US | disclosed |
| US-20170158697-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2017-06-08 | — | — | US | disclosed |
| WO-2015077866-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2015-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158697-A1 | Protein Kinase Inhibitors | TEC, LCK, SRC | PIP4K2A 335/4885PRMT5 792/4885WDR77 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.