Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP5C | P53041 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19659744 | 0.80 | EPHX2 (0.39) | PPP5CEPHX2GBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27098020 | 0.79 | ADRB2 (0.35) | PPP5CEPHX2GBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16449108 | 0.79 | ADRB2 (0.35) | PPP5CEPHX2GBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25578790 | 0.79 | EPHX2 (0.38) | PPP5CEPHX2GBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10692609 | 0.78 | GBA1 (0.46) | EPHX2GBA1ALDH1A1TSHRTDP1 | |
| SCHEMBL15948615 | 0.77 | GBA1 (0.42) | PPP5CEPHX2GBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17342220 | 0.77 | GBA1 (0.42) | PPP5CEPHX2GBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11943576 | 0.77 | GBA1 (0.42) | PPP5CEPHX2GBA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7702633 | 0.77 | ADRB2 (0.39) | PPP5CEPHX2GBA1SMN1; SMN2ADRB2 | |
| SCHEMBL16769690 | 0.77 | GBA1 (0.42) | PPP5CEPHX2GBA1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015077866-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2015-06-04 | — | — | WO | disclosed |