Phosphoric Acid

Phosphoric Acid

SCHEMBL1677253

CC(=O)O.O=P(O)(O)O.[NaH]

nearest known ligand 0.58

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.58
LCK P06239 1/20 0.58
FYN P06241 1/20 0.58
CA2 P00918 1/20 0.43
LMNA P02545 4/20 0.39
TSHR P16473 2/20 0.37
BLM P54132 2/20 0.37
MEN1 O00255 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
THPO P40225 1/20 0.36
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 1/20 0.35
CA1 P00915 2/20 0.33
ALOX15 P16050 1/20 0.33
PMP22 Q01453 1/20 0.33
SLC34A1 Q06495 1/20 0.31
GRIN2D O15399 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28128431 1.00 FFAR3 (0.58) FFAR3LCKFYNCA2LMNA
Phosphoric Acid SCHEMBL22400297 1.00 FFAR3 (0.58) FFAR3LCKFYNCA2LMNA
Phosphoric Acid SCHEMBL7034163 0.96 FFAR3 (0.54) FFAR3LCKFYNCA2LMNA
Phosphoric Acid SCHEMBL28270538 0.96 FFAR3 (0.54) FFAR3LCKFYNCA2LMNA
Phosphoric Acid SCHEMBL11322625 0.96 FFAR3 (0.54) FFAR3LCKFYNCA2LMNA
Phosphoric Acid SCHEMBL11824225 0.96 FFAR3 (0.54) FFAR3LCKFYNCA2LMNA
Phosphoric Acid SCHEMBL2362458 0.96 FFAR3 (0.54) FFAR3LCKFYNCA2LMNA
Phosphoric Acid SCHEMBL7020663 0.96 FFAR3 (0.64) FFAR3LCKFYNCA2LMNA
Phosphoric Acid SCHEMBL7766361 0.96 FFAR3 (0.64) FFAR3LCKFYNCA2LMNA
Phosphoric Acid SCHEMBL14691132 0.96 FFAR3 (0.64) FFAR3LCKFYNCA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110698480-B Synthesis and purification method of ertapenem intermediate 武汉启瑞药业有限公司 2023-09-08 CN claimed
CN-110698480-A Synthesis and purification method of ertapenem intermediate 武汉启瑞药业有限公司 2020-01-17 CN claimed
US-8802416-B2 Thermostable organic solvent tolerant protease from gram-positive bacteria UNIVERSITI PUTRA MALAYSIA (MY) 2014-08-12 US claimed
CN-101565393-B 3-(substituted bisulfonyl fluromethane)-1-propylene compound, synthetic method and applications thereof SHANGHAI INST ORGANIC CHEM 2013-01-23 CN claimed
US-20110097784-A1 THERMOSTABLE ORGANIC SOLVENT TOLERANT PROTEASE FROM GRAM-POSITIVE BACTERIA UNIVERSITI PUTRA MALAYSIA 2011-04-28 US claimed
CN-101565393-A 3-(substituted bisulfonyl fluromethane)-1-propylene compound, synthetic method and applications thereof SHANGHAI INST FOR ORGANIC CHEM (CN) 2009-10-28 CN claimed
CN-118213508-A Silicon-carbon composite material, negative plate and battery 珠海冠宇电池股份有限公司 2024-06-18 CN disclosed
CN-117881402-A Nucleotide and nucleoside therapeutic compositions, combinations, and uses related thereto 埃默里大学 2024-04-12 CN disclosed
CN-110698480-B Synthesis and purification method of ertapenem intermediate 武汉启瑞药业有限公司 2023-09-08 CN disclosed
CN-112931505-A Phthalic dicarboxaldehyde disinfectant, preparation method and application thereof 海韵一剑大卫生科技有限公司 2021-06-11 CN disclosed
CN-110698480-A Synthesis and purification method of ertapenem intermediate 武汉启瑞药业有限公司 2020-01-17 CN disclosed
CN-105997719-B A kind of natural bacteriostatic toothpaste 百草堂医药股份有限公司 2019-03-01 CN disclosed
CN-108125835-A A kind of inflammation-diminishing toothpaste 青岛赛泽网络科技有限公司 2018-06-08 CN disclosed
CN-106580850-A Pain-alleviating toothpaste 广东康绿宝科技实业有限公司 2017-04-26 CN disclosed
CN-106580772-A Toothpaste with effect of reducing internal heat 广东康绿宝科技实业有限公司 2017-04-26 CN disclosed
CN-106551850-A A kind of promoting and tooth-building toothpaste 广东康绿宝科技实业有限公司 2017-04-05 CN disclosed
US-8802416-B2 Thermostable organic solvent tolerant protease from gram-positive bacteria UNIVERSITI PUTRA MALAYSIA (MY) 2014-08-12 US disclosed
US-20110097784-A1 THERMOSTABLE ORGANIC SOLVENT TOLERANT PROTEASE FROM GRAM-POSITIVE BACTERIA UNIVERSITI PUTRA MALAYSIA 2011-04-28 US disclosed
WO-2008112156-A1 CHEMOKINE RECEPTOR MODULATORS ALTIRIS THERAPEUTICS (US) 2008-09-18 WO disclosed
WO-2008109154-A1 CHEMOKINE RECEPTOR MODULATORS ALTIRIS THERAPEUTICS, INC. (US) 2008-09-12 WO disclosed