Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16773498 | 0.91 | HDAC6 (0.43) | HDAC6BCHEMAOANOX1L3MBTL1 | |
| SCHEMBL11978698 | 0.91 | HDAC6 (0.44) | HDAC6BCHEMAOANOX1LMNA | |
| SCHEMBL23555415 | 0.88 | HDAC6 (0.50) | HDAC6BCHEMAOANOX1KMT2A | |
| SCHEMBL12433655 | 0.86 | NPC1 (0.40) | HDAC6BCHEMAOALMNAMAPT | |
| SCHEMBL4243905 | 0.86 | HDAC6 (0.54) | HDAC6BCHEMAOANOX1LMNA | |
| SCHEMBL30436360 | 0.86 | HDAC6 (0.54) | HDAC6BCHEMAOANOX1LMNA | |
| SCHEMBL19785013 | 0.82 | BCHE (0.42) | HDAC6BCHEMAOANOX1LMNA | |
| SCHEMBL8183708 | 0.82 | HDAC6 (0.54) | HDAC6BCHEMAOANOX1MGLL | |
| SCHEMBL29617992 | 0.82 | HDAC6 (0.54) | HDAC6BCHEMAOANOX1MGLL | |
| SCHEMBL15470447 | 0.82 | HDAC6 (0.57) | HDAC6BCHEMAOANOX1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| EP-2858980-B1 | PHENANTHRENES FOR USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-06-26 | — | — | EP | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | PAH, CYP1A1, AHR | HDAC6 4672/4885BCHE 735/4885MAOA 422/4885 |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | HDAC6 4672/4885BCHE 735/4885MAOA 422/4885 |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | HDAC6 4672/4885BCHE 735/4885MAOA 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.