SCHEMBL16773355

SCHEMBL16773355

c1ccc(N(c2ccccc2)c2cccc(-n3c4cc(N(c5ccccc5)c5ccccc5)ccc4c4c3ccc3c5ccccc5n(-c5ccccc5)c34)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.43
▸ ATM Q13315 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ JAK2 O60674 1/20 0.34
▸ JAK3 P52333 1/20 0.34
▸ MAPK8 P45983 1/20 0.30
▸ KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16773634 0.95 KDM4E (0.45) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL9956461 0.95 KDM4E (0.44) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL15582829 0.94 KDM4E (0.44) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL24425586 0.91 L3MBTL1 (0.43) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL17189529 0.90 KDM4E (0.50) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL31795 0.90 KDM4E (0.50) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL16773354 0.90 L3MBTL1 (0.40) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL16870118 0.89 KDM4E (0.41) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL15582828 0.89 KDM4E (0.46) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL10027541 0.89 KDM4E (0.46) KDM4EATML3MBTL1JAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150155498-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME ROHM & HAAS ELECT MAT (KR) 2015-06-04 — — US disclosed
US-20150155498-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME ROHM & HAAS ELECT MAT (KR) 2015-06-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150155498-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME OCIAD2, OCIAD1, OR10J3 KDM4E 1781/4885ATM 4244/4885L3MBTL1 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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