Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.36 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450786 | 0.95 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 | |
| SCHEMBL2609914 | 0.95 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 | |
| SCHEMBL20407304 | 0.89 | PDK2 (0.48) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 | |
| SCHEMBL782290 | 0.89 | PDK2 (0.51) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 | |
| SCHEMBL12950969 | 0.89 | PDK2 (0.51) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 | |
| SCHEMBL29462256 | 0.89 | PDK2 (0.51) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 | |
| SCHEMBL14316663 | 0.87 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 | |
| SCHEMBL23621143 | 0.87 | PDK2 (0.41) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 | |
| SCHEMBL31695395 | 0.87 | PDK2 (0.41) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 | |
| SCHEMBL23168904 | 0.87 | PDK2 (0.46) | ALDH1A1CYP3A4HSD17B10HPGDPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| EP-2858980-B1 | PHENANTHRENES FOR USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-06-26 | — | — | EP | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | PAH, CYP1A1, AHR | ALDH1A1 1334/4885CYP3A4 22/4885HSD17B10 1425/4885 |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | ALDH1A1 1334/4885CYP3A4 22/4885HSD17B10 1425/4885 |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | ALDH1A1 1334/4885CYP3A4 22/4885HSD17B10 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.