Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 1.00 |
| ▸ | TMIGD3 | P0DMS9 | 5/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.84 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774388 | 1.00 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL25566679 | 1.00 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL25566683 | 0.91 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL16774384 | 0.91 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL16774389 | 0.91 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL25566675 | 0.90 | ADORA3 (0.82) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL20122079 | 0.87 | ADORA3 (0.77) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL20122073 | 0.86 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL16774179 | 0.86 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A | |
| SCHEMBL20122157 | 0.84 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015080940-A1 | A3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-06-04 | — | — | WO | disclosed |