Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921046 | 0.89 | HTR6 (0.40) | HTR6HRH1SIGMAR1MCHR1 | |
| SCHEMBL6920818 | 0.85 | HTR6 (0.40) | HTR6HRH1MCHR1 | |
| SCHEMBL6921940 | 0.84 | HTR6 (0.37) | HTR6HRH1MCHR1 | |
| SCHEMBL13834003 | 0.84 | HTR6 (0.39) | HTR6HRH1 | |
| SCHEMBL15087610 | 0.83 | HTR6 (0.36) | HTR6HRH1 | |
| SCHEMBL13394766 | 0.83 | HRH1 (0.56) | HTR6HRH1SIGMAR1 | |
| SCHEMBL2814942 | 0.83 | HTR6 (0.40) | HTR6SIGMAR1MCHR1 | |
| SCHEMBL6922091 | 0.83 | HTR6 (0.36) | HTR6HRH1MCHR1 | |
| SCHEMBL6921358 | 0.81 | HTR6 (0.40) | HTR6HRH1SIGMAR1 | |
| SCHEMBL13833926 | 0.80 | HTR6 (0.39) | HTR6HRH1SIGMAR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051314-B2 | Bridged heterocyclic compounds and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-9051314-B2 | Bridged heterocyclic compounds and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-06-09 | — | — | US | disclosed |