Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 4/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628139 | 0.83 | KISS1R (0.59) | KISS1RSLC1A2GRIK1SLC1A1GRIK2 | |
| SCHEMBL3838853 | 0.83 | KISS1R (0.59) | KISS1RSLC1A2GRIK1SLC1A1GRIK2 | |
| SCHEMBL5672721 | 0.82 | KISS1R (0.61) | KISS1RTDP1SLC1A3SLC1A2CPA1 | |
| SCHEMBL9766489 | 0.82 | HDAC1 (0.60) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL20490025 | 0.81 | CHRM1 (0.48) | KISS1RHDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL7432854 | 0.81 | CHRM1 (0.48) | KISS1RHDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL2491997 | 0.81 | CHRM1 (0.68) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL3657031 | 0.80 | KISS1R (0.50) | KISS1RTDP1TSHRSLC1A3SLC1A2 | |
| SCHEMBL27527680 | 0.79 | KISS1R (0.59) | KISS1RTDP1SLC1A3SLC1A2CPA1 | |
| Ammonia Solution, Strong SCHEMBL27748255 | 0.79 | KISS1R (0.59) | KISS1RTDP1SLC1A3SLC1A2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239057-B1 | Asymmetric catalyst and process for preparing optically active alcohols using the same | KANTO KAGAKU (JP) | 2015-06-03 | — | — | EP | disclosed |