Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042604 | 0.76 | MAPT (0.52) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL1644942 | 0.75 | HIF1A (0.57) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL4839678 | 0.72 | HIF1A (0.63) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL10630540 | 0.72 | KMT2A (0.56) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL19500869 | 0.72 | HIF1A (0.62) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL713040 | 0.72 | PTGIR (0.51) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL16106421 | 0.72 | MAPT (0.58) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL1599724 | 0.71 | PRKDC (0.57) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL16776764 | 0.71 | MAPK14 (0.43) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL4766240 | 0.71 | HIF1A (0.59) | KMT2AMEN1HCRTR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166483-A1 | KINASE INHIBITORS | RESPIVERT LTD (GB) | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166483-A1 | KINASE INHIBITORS | LCK, SYK, FYN | KMT2A 3511/4885MEN1 4840/4885HCRTR1 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.