Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601280 | 0.91 | PAX8 (0.50) | PTGIRPAX8TLR9NPSR1SMN1; SMN2 | |
| SCHEMBL31393778 | 0.88 | PAX8 (0.56) | PTGIRTRPM8PAX8TLR9NPSR1 | |
| SCHEMBL22879499 | 0.86 | PTGIR (0.49) | PTGIRTRPM8PAX8TLR9NPSR1 | |
| SCHEMBL28773371 | 0.85 | PTGIR (0.48) | PTGIRTRPM8PAX8TLR9NPSR1 | |
| SCHEMBL1720515 | 0.83 | KDM4E (0.43) | PTGIRTRPM8NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL5028856 | 0.80 | PTGIR (0.50) | PTGIRTRPM8PAX8NPSR1SMN1; SMN2 | |
| SCHEMBL16776764 | 0.79 | MAPK14 (0.43) | NPSR1SMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL22879480 | 0.78 | PAX8 (0.52) | PTGIRPAX8TLR9NPSR1SMN1; SMN2 | |
| SCHEMBL30743858 | 0.78 | PAX8 (0.52) | PTGIRPAX8TLR9NPSR1SMN1; SMN2 | |
| SCHEMBL8779753 | 0.78 | TSPO (0.53) | PAX8TLR9SMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124807-B2 | Sulfonyl-substituted 6-membered ring derivative | MSD K.K. (JP) | 2012-02-28 | — | — | US | disclosed |