⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544025 | 0.78 | — | — | |
| SCHEMBL4601458 | 0.73 | — | — | |
| SCHEMBL245746 | 0.70 | — | — | |
| SCHEMBL6852731 | 0.70 | — | — | |
| SCHEMBL8304550 | 0.70 | — | — | |
| SCHEMBL10544934 | 0.70 | — | — | |
| SCHEMBL3679400 | 0.67 | TSHR (0.46) | — | |
| SCHEMBL562402 | 0.67 | — | — | |
| SCHEMBL13731004 | 0.67 | LMNA (0.36) | — | |
| SCHEMBL14968279 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174318-A | USING A TRIALKYL- OR TRIALKYLAMINOPHOSPHINE AS REDUCING AGENT | GLAXO LABORATORIES LTD. (GB) | 1979-11-13 | — | — | US | claimed |
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20100076003-A1 | 5-OXAZOLIDIN-2-ONE SUBSTITUTED 1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE DERIVATIVES USEFUL AS ORL-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-03-25 | — | — | US | disclosed |
| US-20090093473-A1 | Spiro-benzimidazoles as inhibitors of gastric acid secretion | NYCOMED GMBH (DE) | 2009-04-09 | — | — | US | disclosed |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080119510-A1 | Substituted Imidazo [4,5-B] Pyridines As Inhibitors Of Gastric Acid Secretion | ALTANA PHARMA AG (DE) | 2008-05-22 | — | — | US | disclosed |
| US-7326718-B2 | 8-Substituted imidazopyridines | ALTANA PHARMA AG (DE) | 2008-02-05 | — | — | US | disclosed |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |
| EP-1764075-A1 | TISSUE FACTOR PRODUCTION INHIBITOR | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
| US-20040235882-A1 | Amino-substituted imidazopyridines for the treatment of gastrointestial diseases | ALTANA PHARMA AG (DE) | 2004-11-25 | — | — | US | disclosed |
| US-20040214852-A1 | Polysubstituted imidazopyridines | ALTANA PHARMA AG (DE) | 2004-10-28 | — | — | US | disclosed |
| WO-2004054984-A1 | 4-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | ALTANA PHARMA AG (DE) | 2004-07-01 | — | — | WO | disclosed |
| WO-2004046144-A1 | 8-SUBSTITUTED IMIDAZOPYRIDINES | ALTANA PHARMA AG (DE) | 2004-06-03 | — | — | WO | disclosed |
| US-20040106642-A1 | POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS | ALTANA PHARMA AG (DE) | 2004-06-03 | — | — | US | disclosed |
| EP-1419156-A1 | ALKYL-SUBSTITUTED IMIDAZOPYRIDINES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | ALTANA Pharma AG (DE) | 2004-05-19 | — | — | EP | disclosed |
| EP-1173439-B1 | HALOALKOXY IMIDAZONAPHTHYRIDINES | ALTANA PHARMA AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2003016310-A1 | ALKYL-SUBSTITUTED IMIDAZOPYRIDINES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | ALTANA PHARMA AG (DE) | 2003-02-27 | — | — | WO | disclosed |
| US-6503923-B1 | Prevention and treatment of gastrointestinal disorders | ALTANA PHARMA AG (DE) | 2003-01-07 | — | — | US | disclosed |
| US-4174318-A | USING A TRIALKYL- OR TRIALKYLAMINOPHOSPHINE AS REDUCING AGENT | GLAXO LABORATORIES LTD. (GB) | 1979-11-13 | — | — | US | disclosed |